rs11071334

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0278 (8332/29936,GnomAD)
C=0269 (1349/5008,1000G)
C=0333 (1282/3854,ALSPAC)
C=0341 (1263/3708,TWINSUK)
chr15:57586613 (GRCh38.p7) (15q21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
101 Enhancers around
8 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.57586613T>C
GRCh37.p13 chr 15NC_000015.9:g.57878811T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.823C=0.177
1000GenomesAmericanSub694T=0.770C=0.230
1000GenomesEast AsianSub1008T=0.639C=0.361
1000GenomesEuropeSub1006T=0.677C=0.323
1000GenomesGlobalStudy-wide5008T=0.731C=0.269
1000GenomesSouth AsianSub978T=0.730C=0.270
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.667C=0.333
The Genome Aggregation DatabaseAfricanSub8720T=0.800C=0.200
The Genome Aggregation DatabaseAmericanSub838T=0.750C=0.250
The Genome Aggregation DatabaseEast AsianSub1618T=0.679C=0.321
The Genome Aggregation DatabaseEuropeSub18458T=0.688C=0.311
The Genome Aggregation DatabaseGlobalStudy-wide29936T=0.721C=0.278
The Genome Aggregation DatabaseOtherSub302T=0.640C=0.360
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.659C=0.341
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs110713340.00046alcohol dependence(early age of onset)20201924
rs110713340.00098alcohol dependence20201924

eQTL of rs11071334 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11071334 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr155782908957829608E067-49203
chr155782965057829700E067-49111
chr155782984757829924E067-48887
chr155782993157830010E067-48801
chr155784641257847278E067-31533
chr155784735557847395E067-31416
chr155784740457847978E067-30833
chr155791899557919271E06740184
chr155782898257829072E068-49739
chr155782908957829608E068-49203
chr155782965057829700E068-49111
chr155782984757829924E068-48887
chr155782993157830010E068-48801
chr155783014957830243E068-48568
chr155783034057830559E068-48252
chr155784199657842564E068-36247
chr155784274157843198E068-35613
chr155784326857843462E068-35349
chr155784525757845392E068-33419
chr155784543757845509E068-33302
chr155784553357846018E068-32793
chr155784602257846166E068-32645
chr155784641257847278E068-31533
chr155784735557847395E068-31416
chr155784740457847978E068-30833
chr155788099057881070E0682179
chr155788118357881273E0682372
chr155788134457881423E0682533
chr155791899557919271E06840184
chr155782908957829608E069-49203
chr155784199657842564E069-36247
chr155784326857843462E069-35349
chr155784553357846018E069-32793
chr155784602257846166E069-32645
chr155784641257847278E069-31533
chr155784735557847395E069-31416
chr155789644757897249E06917636
chr155784641257847278E070-31533
chr155791865757918798E07039846
chr155791899557919271E07040184
chr155792740157927490E07048590
chr155792757257928252E07048761
chr155782898257829072E071-49739
chr155782908957829608E071-49203
chr155784274157843198E071-35613
chr155784326857843462E071-35349
chr155784495157845186E071-33625
chr155784543757845509E071-33302
chr155784553357846018E071-32793
chr155784602257846166E071-32645
chr155784641257847278E071-31533
chr155784735557847395E071-31416
chr155784740457847978E071-30833
chr155788155357882255E0712742
chr155788225657882367E0713445
chr155789644757897249E07117636
chr155782908957829608E072-49203
chr155782965057829700E072-49111
chr155782984757829924E072-48887
chr155782993157830010E072-48801
chr155783014957830243E072-48568
chr155783034057830559E072-48252
chr155783436057834902E072-43909
chr155784602257846166E072-32645
chr155784641257847278E072-31533
chr155784735557847395E072-31416
chr155784740457847978E072-30833
chr155782898257829072E073-49739
chr155782908957829608E073-49203
chr155784326857843462E073-35349
chr155784349557843896E073-34915
chr155784553357846018E073-32793
chr155784602257846166E073-32645
chr155784641257847278E073-31533
chr155789644757897249E07317636
chr155782984757829924E074-48887
chr155784641257847278E074-31533
chr155784735557847395E074-31416
chr155784740457847978E074-30833
chr155785897757859508E074-19303
chr155788055857880944E0741747
chr155788099057881070E0742179
chr155788118357881273E0742372
chr155788134457881423E0742533
chr155791196257912302E07433151
chr155791232757912407E07433516
chr155791899557919271E07440184
chr155783418957834348E081-44463
chr155783436057834902E081-43909
chr155784641257847278E081-31533
chr155792757257928252E08148761
chr155784602257846166E082-32645
chr155784641257847278E082-31533
chr155784735557847395E082-31416
chr155784740457847978E082-30833
chr155792716557927209E08248354
chr155792725657927365E08248445
chr155792740157927490E08248590
chr155792757257928252E08248761
chr155792846857928518E08249657
chr155792874457928794E08249933










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr155788335657885099E0674545
chr155788335657885099E0684545
chr155788335657885099E0694545
chr155788335657885099E0714545
chr155788335657885099E0724545
chr155788335657885099E0734545
chr155788335657885099E0744545
chr155788335657885099E0824545