rs11071587

Homo sapiens
G>A
RORA : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0376 (11259/29910,GnomAD)
A=0348 (10159/29118,TOPMED)
A=0330 (1651/5008,1000G)
A=0444 (1710/3854,ALSPAC)
A=0449 (1665/3708,TWINSUK)
chr15:61141344 (GRCh38.p7) (15q22.2)
AD
GWASdb2
1   publication(s)
See rs on genome
139 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.61141344G>A
GRCh37.p13 chr 15NC_000015.9:g.61433543G>A
RORA RefSeqGeneNG_029246.1:g.92960C>T

Gene: RORA, RAR related orphan receptor A(minus strand)

Molecule type Change Amino acid[Codon] SO Term
RORA transcript variant 1NM_134261.2:c.N/AIntron Variant
RORA transcript variant 3NM_002943.3:c.N/AGenic Upstream Transcript Variant
RORA transcript variant 2NM_134260.2:c.N/AGenic Upstream Transcript Variant
RORA transcript variant 4NM_134262.2:c.N/AGenic Upstream Transcript Variant
RORA transcript variant X6XM_011521878.1:c.N/AIntron Variant
RORA transcript variant X3XM_005254584.4:c.N/AGenic Upstream Transcript Variant
RORA transcript variant X1XM_011521874.1:c.N/AGenic Upstream Transcript Variant
RORA transcript variant X2XM_011521875.1:c.N/AGenic Upstream Transcript Variant
RORA transcript variant X4XM_011521877.2:c.N/AGenic Upstream Transcript Variant
RORA transcript variant X8XM_011521879.2:c.N/AGenic Upstream Transcript Variant
RORA transcript variant X5XM_017022466.1:c.N/AGenic Upstream Transcript Variant
RORA transcript variant X7XM_017022467.1:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.818A=0.182
1000GenomesAmericanSub694G=0.730A=0.270
1000GenomesEast AsianSub1008G=0.528A=0.472
1000GenomesEuropeSub1006G=0.582A=0.418
1000GenomesGlobalStudy-wide5008G=0.670A=0.330
1000GenomesSouth AsianSub978G=0.670A=0.330
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.556A=0.444
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.651A=0.348
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.551A=0.449
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs110715870.000871alcohol dependence21314694

eQTL of rs11071587 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11071587 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr156138385361383949E067-49594
chr156138876761388914E067-44629
chr156138899361389086E067-44457
chr156138931261389463E067-44080
chr156138957961389662E067-43881
chr156139013761390197E067-43346
chr156141486861414960E067-18583
chr156141615961416219E067-17324
chr156141624961416309E067-17234
chr156144411661444255E06710573
chr156144442761444521E06710884
chr156144488161444921E06711338
chr156144504061445116E06711497
chr156146091461461033E06727371
chr156146104161461118E06727498
chr156146122961462043E06727686
chr156146357161463707E06730028
chr156147903561479867E06745492
chr156139585361395980E068-37563
chr156139603161396071E068-37472
chr156139607661396223E068-37320
chr156139623961396289E068-37254
chr156139629361396366E068-37177
chr156139639861396521E068-37022
chr156140731161407361E068-26182
chr156140739961407480E068-26063
chr156140757061407722E068-25821
chr156144411661444255E06810573
chr156144442761444521E06810884
chr156144990961451100E06816366
chr156146091461461033E06827371
chr156146104161461118E06827498
chr156146122961462043E06827686
chr156146216361462776E06828620
chr156146297461463385E06829431
chr156147891861478968E06845375
chr156138876761388914E069-44629
chr156138899361389086E069-44457
chr156138931261389463E069-44080
chr156138957961389662E069-43881
chr156139623961396289E069-37254
chr156139629361396366E069-37177
chr156140731161407361E069-26182
chr156144002461440074E0696481
chr156144411661444255E06910573
chr156144488161444921E06911338
chr156144504061445116E06911497
chr156144990961451100E06916366
chr156146122961462043E06927686
chr156146216361462776E06928620
chr156138385361383949E070-49594
chr156143834561439331E0704802
chr156143985561439905E0706312
chr156144002461440074E0706481
chr156144020261440317E0706659
chr156144561461445726E07012071
chr156147903561479867E07045492
chr156147991761480001E07046374
chr156138899361389086E071-44457
chr156138931261389463E071-44080
chr156144411661444255E07110573
chr156146216361462776E07128620
chr156147903561479867E07145492
chr156138899361389086E072-44457
chr156138931261389463E072-44080
chr156138957961389662E072-43881
chr156139483361394901E072-38642
chr156141551261415596E072-17947
chr156141593961415993E072-17550
chr156141615961416219E072-17324
chr156141624961416309E072-17234
chr156141659461416648E072-16895
chr156144002461440074E0726481
chr156144020261440317E0726659
chr156144048861440538E0726945
chr156144990961451100E07216366
chr156147891861478968E07245375
chr156147991761480001E07246374
chr156148006961480218E07246526
chr156148035261480506E07246809
chr156138931261389463E073-44080
chr156138957961389662E073-43881
chr156139013761390197E073-43346
chr156140803461408229E073-25314
chr156140867661408827E073-24716
chr156141525061415317E073-18226
chr156141551261415596E073-17947
chr156144411661444255E07310573
chr156144442761444521E07310884
chr156144488161444921E07311338
chr156144504061445116E07311497
chr156147729261477342E07343749
chr156148006961480218E07346526
chr156148035261480506E07346809
chr156138899361389086E074-44457
chr156138931261389463E074-44080
chr156138957961389662E074-43881
chr156139526561395352E074-38191
chr156139535661395455E074-38088
chr156139607661396223E074-37320
chr156139623961396289E074-37254
chr156139629361396366E074-37177
chr156141413161414406E074-19137
chr156141486861414960E074-18583
chr156141525061415317E074-18226
chr156141551261415596E074-17947
chr156141593961415993E074-17550
chr156141615961416219E074-17324
chr156141624961416309E074-17234
chr156144411661444255E07410573
chr156144442761444521E07410884
chr156144488161444921E07411338
chr156144504061445116E07411497
chr156144561461445726E07412071
chr156146104161461118E07427498
chr156146122961462043E07427686
chr156146216361462776E07428620
chr156146297461463385E07429431
chr156147903561479867E07445492
chr156141525061415317E081-18226
chr156141551261415596E081-17947
chr156142016761420211E081-13332
chr156142026161420305E081-13238
chr156142032261420372E081-13171
chr156142062761421168E081-12375
chr156143834561439331E0814802
chr156143950861439569E0815965
chr156143971361439763E0816170
chr156143985561439905E0816312
chr156144002461440074E0816481
chr156138385361383949E082-49594
chr156138411761384214E082-49329
chr156138424361384330E082-49213
chr156142016761420211E082-13332
chr156142026161420305E082-13238
chr156142032261420372E082-13171
chr156142062761421168E082-12375
chr156143834561439331E0824802
chr156147903561479867E08245492