SNP Detail Info-rs11076221

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0085 (2552/29970,GnomAD)
A==0094 (2747/29118,TOPMED)
A==0096 (481/5008,1000G)
A==0074 (287/3854,ALSPAC)
A==0077 (285/3708,TWINSUK)

Position: chr16:51927631 (GRCh38.p7) (16q12.1)

Phenotype: AD

Dataset:

GWASCatalog

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 19 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 16	NC_000016.10:g.51927631A>G
GRCh37.p13 chr 16	NC_000016.9:g.51961543A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.156	G=0.844
1000Genomes	American	Sub	694	A=0.030	G=0.970
1000Genomes	East Asian	Sub	1008	A=0.092	G=0.908
1000Genomes	Europe	Sub	1006	A=0.066	G=0.934
1000Genomes	Global	Study-wide	5008	A=0.096	G=0.904
1000Genomes	South Asian	Sub	978	A=0.100	G=0.900
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.074	G=0.926
The Genome Aggregation Database	African	Sub	8714	A=0.148	G=0.852
The Genome Aggregation Database	American	Sub	838	A=0.040	G=0.960
The Genome Aggregation Database	East Asian	Sub	1620	A=0.111	G=0.889
The Genome Aggregation Database	Europe	Sub	18496	A=0.055	G=0.944
The Genome Aggregation Database	Global	Study-wide	29970	A=0.085	G=0.914
The Genome Aggregation Database	Other	Sub	302	A=0.060	G=0.940
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.094	G=0.905
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.077	G=0.923

PMID	Title	Author	Journal
26365420	The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores.	Mbarek H	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs11076221	9E-06	alcohol dependence	26365420

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr16	51972877	51973815	E070	11334
chr16	51974039	51974079	E070	12496
chr16	51974167	51974533	E070	12624
chr16	52001279	52001349	E070	39736
chr16	52001439	52001511	E070	39896
chr16	52001579	52001923	E070	40036
chr16	52002232	52002292	E070	40689
chr16	52002383	52002464	E070	40840
chr16	52002786	52002894	E070	41243
chr16	51972877	51973815	E081	11334
chr16	51974039	51974079	E081	12496
chr16	51974167	51974533	E081	12624
chr16	52001439	52001511	E081	39896
chr16	52001579	52001923	E081	40036
chr16	51972877	51973815	E082	11334
chr16	51974039	51974079	E082	12496
chr16	51987393	51987530	E082	25850
chr16	52001579	52001923	E082	40036
chr16	52005750	52006185	E082	44207

rs11076221