rs11078278

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0467 (13977/29890,GnomAD)
T==0419 (12220/29118,TOPMED)
T==0418 (2095/5008,1000G)
C=0467 (1799/3854,ALSPAC)
C=0488 (1810/3708,TWINSUK)
chr17:15090684 (GRCh38.p7) (17p12)
AD
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.15090684T>C
GRCh37.p13 chr 17NC_000017.10:g.14994001T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.319C=0.681
1000GenomesAmericanSub694T=0.490C=0.510
1000GenomesEast AsianSub1008T=0.390C=0.610
1000GenomesEuropeSub1006T=0.486C=0.514
1000GenomesGlobalStudy-wide5008T=0.418C=0.582
1000GenomesSouth AsianSub978T=0.460C=0.540
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.533C=0.467
The Genome Aggregation DatabaseAfricanSub8702T=0.331C=0.669
The Genome Aggregation DatabaseAmericanSub836T=0.530C=0.470
The Genome Aggregation DatabaseEast AsianSub1612T=0.426C=0.574
The Genome Aggregation DatabaseEuropeSub18438T=0.534C=0.465
The Genome Aggregation DatabaseGlobalStudy-wide29890T=0.467C=0.532
The Genome Aggregation DatabaseOtherSub302T=0.380C=0.620
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.419C=0.580
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.512C=0.488
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs110782780.00055alcohol dependence20201924

eQTL of rs11078278 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11078278 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr171498916214989221E070-4780
chr171498930114989365E070-4636
chr171498942114989477E070-4524
chr171498958214989721E070-4280
chr171498974614990301E070-3700
chr171499033614990456E070-3545
chr171499109014991296E070-2705
chr171499130714991632E070-2369
chr171498942114989477E081-4524
chr171498958214989721E081-4280
chr171498974614990301E081-3700
chr171499033614990456E081-3545
chr171501607115017031E08122070
chr171501607115017031E08222070