rs11084394

Homo sapiens
T>C
TMEM150B : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0100 (2996/29948,GnomAD)
T==0113 (3313/29118,TOPMED)
T==0094 (471/5008,1000G)
T==0097 (372/3854,ALSPAC)
T==0096 (357/3708,TWINSUK)
chr19:55330677 (GRCh38.p7) (19q13.42)
AD
GWASdb2
1   publication(s)
See rs on genome
128 Enhancers around
42 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 19NC_000019.10:g.55330677T>C
GRCh37.p13 chr 19NC_000019.9:g.55842045T>C

Gene: TMEM150B, transmembrane protein 150B(minus strand)

Molecule type Change Amino acid[Codon] SO Term
TMEM150B transcript variant 2NM_001085488.2:c.N/AGenic Upstream Transcript Variant
TMEM150B transcript variant 1NM_001282011.1:c.N/AGenic Upstream Transcript Variant
TMEM150B transcript variant 3NR_104066.1:n.N/AGenic Upstream Transcript Variant
TMEM150B transcript variant 4NR_104071.1:n.N/AGenic Upstream Transcript Variant
TMEM150B transcript variant X2XM_005258812.3:c.N/AIntron Variant
TMEM150B transcript variant X8XM_011526850.2:c.N/AIntron Variant
TMEM150B transcript variant X11XM_011526851.2:c.N/AIntron Variant
TMEM150B transcript variant X1XM_011526852.2:c.N/AIntron Variant
TMEM150B transcript variant X3XM_011526853.2:c.N/AIntron Variant
TMEM150B transcript variant X6XM_011526855.2:c.N/AIntron Variant
TMEM150B transcript variant X4XM_017026667.1:c.N/AIntron Variant
TMEM150B transcript variant X5XM_011526854.2:c.N/AGenic Upstream Transcript Variant
TMEM150B transcript variant X7XM_011526856.2:c.N/AGenic Upstream Transcript Variant
TMEM150B transcript variant X9XM_011526857.2:c.N/AGenic Upstream Transcript Variant
TMEM150B transcript variant X10XM_017026668.1:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.110C=0.890
1000GenomesAmericanSub694T=0.050C=0.950
1000GenomesEast AsianSub1008T=0.110C=0.890
1000GenomesEuropeSub1006T=0.087C=0.913
1000GenomesGlobalStudy-wide5008T=0.094C=0.906
1000GenomesSouth AsianSub978T=0.090C=0.910
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.097C=0.903
The Genome Aggregation DatabaseAfricanSub8718T=0.103C=0.897
The Genome Aggregation DatabaseAmericanSub838T=0.060C=0.940
The Genome Aggregation DatabaseEast AsianSub1618T=0.107C=0.893
The Genome Aggregation DatabaseEuropeSub18472T=0.100C=0.899
The Genome Aggregation DatabaseGlobalStudy-wide29948T=0.100C=0.900
The Genome Aggregation DatabaseOtherSub302T=0.090C=0.910
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.113C=0.886
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.096C=0.904
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs110843940.00044alcohol dependence(early age of onset)20201924
rs110843940.00066alcohol dependence20201924

eQTL of rs11084394 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11084394 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr195579750955797595E067-44450
chr195579771255797769E067-44276
chr195579814755798191E067-43854
chr195579822055798357E067-43688
chr195579843255798493E067-43552
chr195579915755799238E067-42807
chr195579941255799460E067-42585
chr195580042855800618E067-41427
chr195580062355800753E067-41292
chr195581225455812907E067-29138
chr195585581855856172E06713773
chr195580042855800618E068-41427
chr195580062355800753E068-41292
chr195580088655800996E068-41049
chr195580308055803261E068-38784
chr195580336555803861E068-38184
chr195581155655811765E068-30280
chr195579469255794776E069-47269
chr195579750955797595E069-44450
chr195579771255797769E069-44276
chr195580042855800618E069-41427
chr195580062355800753E069-41292
chr195580088655800996E069-41049
chr195581225455812907E069-29138
chr195583194555831995E069-10050
chr195585581855856172E06913773
chr195579469255794776E070-47269
chr195579750955797595E070-44450
chr195584866155848701E0706616
chr195584871455848879E0706669
chr195584921255849256E0707167
chr195584927255849386E0707227
chr195585370355853924E07011658
chr195585411955854239E07012074
chr195585424755854328E07012202
chr195585436155854495E07012316
chr195585452055854579E07012475
chr195585473455854821E07012689
chr195585484755854897E07012802
chr195585493255855001E07012887
chr195585504555855185E07013000
chr195585522455855411E07013179
chr195585581855856172E07013773
chr195585619955856584E07014154
chr195585680655856964E07014761
chr195585699855857054E07014953
chr195585707055857446E07015025
chr195585750055857599E07015455
chr195585854355858753E07016498
chr195585877355858823E07016728
chr195585912055859174E07017075
chr195585923055859280E07017185
chr195585930655859424E07017261
chr195589056155890952E07048516
chr195579469255794776E071-47269
chr195579750955797595E071-44450
chr195579843255798493E071-43552
chr195580042855800618E071-41427
chr195580062355800753E071-41292
chr195580088655800996E071-41049
chr195580290955803048E071-38997
chr195580336555803861E071-38184
chr195581137155811432E071-30613
chr195581155655811765E071-30280
chr195581225455812907E071-29138
chr195585581855856172E07113773
chr195585619955856584E07114154
chr195585680655856964E07114761
chr195585699855857054E07114953
chr195579750955797595E072-44450
chr195579814755798191E072-43854
chr195579843255798493E072-43552
chr195580042855800618E072-41427
chr195580062355800753E072-41292
chr195580088655800996E072-41049
chr195580336555803861E072-38184
chr195581137155811432E072-30613
chr195581155655811765E072-30280
chr195581225455812907E072-29138
chr195585581855856172E07213773
chr195585619955856584E07214154
chr195585699855857054E07214953
chr195579750955797595E073-44450
chr195579814755798191E073-43854
chr195580042855800618E073-41427
chr195580062355800753E073-41292
chr195580088655800996E073-41049
chr195581126155811315E073-30730
chr195581137155811432E073-30613
chr195581155655811765E073-30280
chr195581225455812907E073-29138
chr195581382355813880E073-28165
chr195585522455855411E07313179
chr195579469255794776E074-47269
chr195579750955797595E074-44450
chr195579771255797769E074-44276
chr195579814755798191E074-43854
chr195579822055798357E074-43688
chr195579843255798493E074-43552
chr195580042855800618E074-41427
chr195580062355800753E074-41292
chr195580088655800996E074-41049
chr195581126155811315E074-30730
chr195581137155811432E074-30613
chr195581155655811765E074-30280
chr195581225455812907E074-29138
chr195585581855856172E07413773
chr195585619955856584E07414154
chr195579469255794776E081-47269
chr195579750955797595E081-44450
chr195579771255797769E081-44276
chr195585356955853677E08111524
chr195585370355853924E08111658
chr195585522455855411E08113179
chr195585581855856172E08113773
chr195579389255794067E082-47978
chr195581225455812907E082-29138
chr195585356955853677E08211524
chr195585370355853924E08211658
chr195585411955854239E08212074
chr195585424755854328E08212202
chr195585436155854495E08212316
chr195585452055854579E08212475
chr195585473455854821E08212689
chr195589007455890301E08248029
chr195589031855890369E08248273
chr195589041255890452E08248367
chr195589056155890952E08248516










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr195579496355795591E067-46454
chr195579575555795820E067-46225
chr195579588255796356E067-45689
chr195584957755853410E0677532
chr195579496355795591E068-46454
chr195579575555795820E068-46225
chr195579588255796356E068-45689
chr195584957755853410E0687532
chr195579496355795591E069-46454
chr195579575555795820E069-46225
chr195579588255796356E069-45689
chr195579926855799381E069-42664
chr195584957755853410E0697532
chr195579496355795591E070-46454
chr195579575555795820E070-46225
chr195579588255796356E070-45689
chr195584957755853410E0707532
chr195579496355795591E071-46454
chr195579575555795820E071-46225
chr195579588255796356E071-45689
chr195584957755853410E0717532
chr195579496355795591E072-46454
chr195579575555795820E072-46225
chr195579588255796356E072-45689
chr195579926855799381E072-42664
chr195583104455831587E072-10458
chr195584957755853410E0727532
chr195579496355795591E073-46454
chr195579575555795820E073-46225
chr195579588255796356E073-45689
chr195584957755853410E0737532
chr195579496355795591E074-46454
chr195579575555795820E074-46225
chr195579588255796356E074-45689
chr195579926855799381E074-42664
chr195584957755853410E0747532
chr195579496355795591E082-46454
chr195579575555795820E082-46225
chr195579588255796356E082-45689
chr195583104455831587E082-10458
chr195584957755853410E0827532
chr195586434155866547E08222296