rs11090754

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0215 (6442/29918,GnomAD)
C=0258 (7523/29114,TOPMED)
C=0180 (903/5008,1000G)
C=0150 (579/3854,ALSPAC)
C=0141 (524/3708,TWINSUK)
chr22:47275457 (GRCh38.p7) (22q13.31)
ND
GWASdb2
1   publication(s)
See rs on genome
43 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 22NC_000022.11:g.47275457T>C
GRCh37.p13 chr 22NC_000022.10:g.47671207T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.533C=0.467
1000GenomesAmericanSub694T=0.900C=0.100
1000GenomesEast AsianSub1008T=0.995C=0.005
1000GenomesEuropeSub1006T=0.877C=0.123
1000GenomesGlobalStudy-wide5008T=0.820C=0.180
1000GenomesSouth AsianSub978T=0.910C=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.850C=0.150
The Genome Aggregation DatabaseAfricanSub8688T=0.553C=0.447
The Genome Aggregation DatabaseAmericanSub836T=0.900C=0.100
The Genome Aggregation DatabaseEast AsianSub1622T=0.999C=0.001
The Genome Aggregation DatabaseEuropeSub18470T=0.868C=0.131
The Genome Aggregation DatabaseGlobalStudy-wide29918T=0.784C=0.215
The Genome Aggregation DatabaseOtherSub302T=0.850C=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29114T=0.741C=0.258
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.859C=0.141
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs110907542.16E-06alcohol and nictotine co-dependence20158304

eQTL of rs11090754 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11090754 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr224764252847642653E067-28554
chr224764291647643309E067-27898
chr224764399647644046E067-27161
chr224764252847642653E068-28554
chr224764291647643309E068-27898
chr224764252847642653E069-28554
chr224764291647643309E069-27898
chr224764399647644046E069-27161
chr224763447147634778E070-36429
chr224763484447634884E070-36323
chr224763492047635018E070-36189
chr224764252847642653E070-28554
chr224764291647643309E070-27898
chr224767148547672118E070278
chr224767224147672291E0701034
chr224767253447672584E0701327
chr224764252847642653E071-28554
chr224764291647643309E071-27898
chr224764399647644046E071-27161
chr224764252847642653E072-28554
chr224764291647643309E072-27898
chr224764399647644046E072-27161
chr224768808247688725E07216875
chr224768880147688928E07217594
chr224768944847689492E07218241
chr224764252847642653E073-28554
chr224764291647643309E073-27898
chr224764399647644046E073-27161
chr224764252847642653E074-28554
chr224764291647643309E074-27898
chr224764399647644046E074-27161
chr224762577747627392E081-43815
chr224762769447627799E081-43408
chr224762822747628657E081-42550
chr224767345647673622E0812249
chr224767371447673782E0812507
chr224767382847673958E0812621
chr224767615047676480E0814943
chr224767659347676643E0815386
chr224767679047676835E0815583
chr224767693747677169E0815730
chr224770319147703333E08131984
chr224770361647703984E08132409