rs11096778

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0477 (14229/29826,GnomAD)
T==0450 (13130/29118,TOPMED)
T==0485 (2428/5008,1000G)
T==0490 (1888/3854,ALSPAC)
T==0481 (1783/3708,TWINSUK)
chr4:35567288 (GRCh38.p7) (4p15.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
14 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.35567288T>C
GRCh37.p13 chr 4NC_000004.11:g.35568910T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.391C=0.609
1000GenomesAmericanSub694T=0.460C=0.540
1000GenomesEast AsianSub1008T=0.703C=0.297
1000GenomesEuropeSub1006T=0.512C=0.488
1000GenomesGlobalStudy-wide5008T=0.485C=0.515
1000GenomesSouth AsianSub978T=0.380C=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.490C=0.510
The Genome Aggregation DatabaseAfricanSub8690T=0.408C=0.592
The Genome Aggregation DatabaseAmericanSub836T=0.410C=0.590
The Genome Aggregation DatabaseEast AsianSub1616T=0.743C=0.257
The Genome Aggregation DatabaseEuropeSub18384T=0.487C=0.512
The Genome Aggregation DatabaseGlobalStudy-wide29826T=0.477C=0.522
The Genome Aggregation DatabaseOtherSub300T=0.570C=0.430
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.450C=0.549
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.481C=0.519
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs110967780.000532nicotine dependence17158188

eQTL of rs11096778 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11096778 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr43552673735526787E074-42123
chr43553670135536912E082-31998
chr43553699835537160E082-31750


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr43552687235526986E068-41924
chr43552703435527236E068-41674
chr43552753335527608E068-41302
chr43552687235526986E069-41924
chr43552703435527236E069-41674
chr43552687235526986E071-41924
chr43552703435527236E071-41674
chr43552753335527608E071-41302
chr43552687235526986E072-41924
chr43552703435527236E072-41674
chr43552687235526986E073-41924
chr43552703435527236E073-41674
chr43552687235526986E074-41924
chr43552703435527236E074-41674