rs11109504

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0376 (11248/29886,GnomAD)
A=0336 (9802/29118,TOPMED)
A=0316 (1582/5008,1000G)
A=0410 (1582/3854,ALSPAC)
A=0413 (1532/3708,TWINSUK)
chr12:78362131 (GRCh38.p7) (12q21.2)
ND
GWASdb2
1   publication(s)
See rs on genome
27 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.78362131G>A
GRCh37.p13 chr 12NC_000012.11:g.78755911G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.736A=0.264
1000GenomesAmericanSub694G=0.710A=0.290
1000GenomesEast AsianSub1008G=0.692A=0.308
1000GenomesEuropeSub1006G=0.596A=0.404
1000GenomesGlobalStudy-wide5008G=0.684A=0.316
1000GenomesSouth AsianSub978G=0.680A=0.320
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.590A=0.410
The Genome Aggregation DatabaseAfricanSub8696G=0.715A=0.285
The Genome Aggregation DatabaseAmericanSub832G=0.750A=0.250
The Genome Aggregation DatabaseEast AsianSub1606G=0.699A=0.301
The Genome Aggregation DatabaseEuropeSub18450G=0.566A=0.433
The Genome Aggregation DatabaseGlobalStudy-wide29886G=0.623A=0.376
The Genome Aggregation DatabaseOtherSub302G=0.720A=0.280
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.663A=0.336
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.587A=0.413
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs111095042.89E-05nicotine smoking19268276

eQTL of rs11109504 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11109504 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr127880052178801035E06944610
chr127872410078724328E081-31583
chr127872439578724447E081-31464
chr127872448878724774E081-31137
chr127872557278725836E081-30075
chr127872600278726055E081-29856
chr127872618578726266E081-29645
chr127876831378768363E08112402
chr127879574478795864E08139833
chr127879590478795954E08139993
chr127879622478796417E08140313
chr127879644678796596E08140535
chr127872410078724328E082-31583
chr127872439578724447E082-31464
chr127872448878724774E082-31137
chr127872486178724927E082-30984
chr127872505578725307E082-30604
chr127872537678725433E082-30478
chr127872557278725836E082-30075
chr127876767478767843E08211763
chr127876789378767949E08211982
chr127876807378768151E08212162
chr127876831378768363E08212402
chr127876856378769035E08212652
chr127879622478796417E08240313
chr127879644678796596E08240535
chr127879663378797437E08240722