rs11112082

Homo sapiens
G>T
CHST11 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0051 (1541/29972,GnomAD)
T=0076 (2217/29118,TOPMED)
T=0056 (278/5008,1000G)
T=0018 (71/3854,ALSPAC)
T=0022 (82/3708,TWINSUK)
chr12:104497619 (GRCh38.p7) (12q23.3)
ND
GWASdb2
1   publication(s)
See rs on genome

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.104497619G>T
GRCh37.p13 chr 12NC_000012.11:g.104891397G>T
CHST11 RefSeqGeneNG_029810.1:g.45706G>T

Gene: CHST11, carbohydrate (chondroitin 4) sulfotransferase 11(plus strand)

Molecule type Change Amino acid[Codon] SO Term
CHST11 transcript variant 2NM_001173982.1:c.N/AIntron Variant
CHST11 transcript variant 1NM_018413.5:c.N/AIntron Variant
CHST11 transcript variant X1XM_017019369.1:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.840T=0.160
1000GenomesAmericanSub694G=0.970T=0.030
1000GenomesEast AsianSub1008G=1.000T=0.000
1000GenomesEuropeSub1006G=0.974T=0.026
1000GenomesGlobalStudy-wide5008G=0.944T=0.056
1000GenomesSouth AsianSub978G=0.980T=0.020
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.982T=0.018
The Genome Aggregation DatabaseAfricanSub8724G=0.862T=0.138
The Genome Aggregation DatabaseAmericanSub838G=0.980T=0.020
The Genome Aggregation DatabaseEast AsianSub1620G=1.000T=0.000
The Genome Aggregation DatabaseEuropeSub18488G=0.983T=0.017
The Genome Aggregation DatabaseGlobalStudy-wide29972G=0.948T=0.051
The Genome Aggregation DatabaseOtherSub302G=1.000T=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.923T=0.076
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.978T=0.022
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs111120820.000753nicotine smoking19268276

eQTL of rs11112082 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11112082 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr12104879947104880042E067-11355
chr12104880120104880613E067-10784
chr12104880678104881066E067-10331
chr12104904031104904421E06712634
chr12104904473104904575E06713076
chr12104912778104913952E06721381
chr12104916823104917796E06725426
chr12104917853104918187E06726456
chr12104849264104849629E068-41768
chr12104857731104857828E068-33569
chr12104858719104859168E068-32229
chr12104862938104863072E068-28325
chr12104863143104863584E068-27813
chr12104866377104866560E068-24837
chr12104866597104866647E068-24750
chr12104866937104867127E068-24270
chr12104867133104867815E068-23582
chr12104879368104879915E068-11482
chr12104879947104880042E068-11355
chr12104880120104880613E068-10784
chr12104880678104881066E068-10331
chr12104881084104881548E068-9849
chr12104881945104882012E068-9385
chr12104882123104882385E068-9012
chr12104882393104882517E068-8880
chr12104887001104887080E068-4317
chr12104887127104887278E068-4119
chr12104887447104887631E068-3766
chr12104889062104889129E068-2268
chr12104889145104889209E068-2188
chr12104889601104889707E068-1690
chr12104898893104899090E0687496
chr12104899095104899180E0687698
chr12104899183104899571E0687786
chr12104899619104899681E0688222
chr12104899729104899789E0688332
chr12104903764104903832E06812367
chr12104903920104904022E06812523
chr12104904031104904421E06812634
chr12104904473104904575E06813076
chr12104905155104905307E06813758
chr12104905315104905365E06813918
chr12104908625104908694E06817228
chr12104908768104908831E06817371
chr12104908899104908949E06817502
chr12104908954104909214E06817557
chr12104909307104909387E06817910
chr12104909467104909532E06818070
chr12104909629104909764E06818232
chr12104913979104914812E06822582
chr12104914818104914991E06823421
chr12104916823104917796E06825426
chr12104917853104918187E06826456
chr12104918484104918609E06827087
chr12104934205104934285E06842808
chr12104934420104934537E06843023
chr12104934630104934716E06843233
chr12104934726104935104E06843329
chr12104935140104935216E06843743
chr12104870749104870907E069-20490
chr12104870999104871136E069-20261
chr12104873485104873702E069-17695
chr12104873729104873795E069-17602
chr12104873819104873894E069-17503
chr12104873901104874024E069-17373
chr12104880120104880613E069-10784
chr12104880678104881066E069-10331
chr12104881084104881548E069-9849
chr12104897091104897189E0695694
chr12104913979104914812E06922582
chr12104914818104914991E06923421
chr12104915091104915151E06923694
chr12104915236104915446E06923839
chr12104915493104915769E06924096
chr12104918484104918609E06927087
chr12104866377104866560E070-24837
chr12104866597104866647E070-24750
chr12104866937104867127E070-24270
chr12104879947104880042E070-11355
chr12104880120104880613E070-10784
chr12104880678104881066E070-10331
chr12104881084104881548E070-9849
chr12104881945104882012E070-9385
chr12104889455104889544E070-1853
chr12104898695104898892E0707298
chr12104898893104899090E0707496
chr12104899095104899180E0707698
chr12104899183104899571E0707786
chr12104900076104900161E0708679
chr12104901346104901717E0709949
chr12104903764104903832E07012367
chr12104903920104904022E07012523
chr12104904031104904421E07012634
chr12104907394104907865E07015997
chr12104907925104908091E07016528
chr12104908148104908245E07016751
chr12104911472104911646E07020075
chr12104911662104911712E07020265
chr12104911718104911774E07020321
chr12104912099104912232E07020702
chr12104912284104912381E07020887
chr12104912441104912694E07021044
chr12104912778104913952E07021381
chr12104913979104914812E07022582
chr12104914818104914991E07023421
chr12104915091104915151E07023694
chr12104915236104915446E07023839
chr12104915493104915769E07024096
chr12104927567104927651E07036170
chr12104927809104927903E07036412
chr12104927997104928560E07036600
chr12104928665104928733E07037268
chr12104928771104928877E07037374
chr12104928950104929054E07037553
chr12104929203104929432E07037806
chr12104934630104934716E07043233
chr12104934726104935104E07043329
chr12104935140104935216E07043743
chr12104938704104938868E07047307
chr12104939002104939083E07047605
chr12104858719104859168E071-32229
chr12104866377104866560E071-24837
chr12104866597104866647E071-24750
chr12104866937104867127E071-24270
chr12104867133104867815E071-23582
chr12104876403104876635E071-14762
chr12104876644104876803E071-14594
chr12104879947104880042E071-11355
chr12104880120104880613E071-10784
chr12104880678104881066E071-10331
chr12104889601104889707E071-1690
chr12104899095104899180E0717698
chr12104901192104901242E0719795
chr12104903764104903832E07112367
chr12104903920104904022E07112523
chr12104904031104904421E07112634
chr12104904473104904575E07113076
chr12104912778104913952E07121381
chr12104916823104917796E07125426
chr12104918828104919091E07127431
chr12104939798104939897E07148401
chr12104866597104866647E072-24750
chr12104866937104867127E072-24270
chr12104880120104880613E072-10784
chr12104880678104881066E072-10331
chr12104903764104903832E07212367
chr12104903920104904022E07212523
chr12104904031104904421E07212634
chr12104913979104914812E07222582
chr12104866377104866560E073-24837
chr12104866597104866647E073-24750
chr12104880678104881066E073-10331
chr12104881084104881548E073-9849
chr12104882123104882385E073-9012
chr12104882393104882517E073-8880
chr12104900424104901172E0739027
chr12104903920104904022E07312523
chr12104904031104904421E07312634
chr12104912778104913952E07321381
chr12104913979104914812E07322582
chr12104879368104879915E074-11482
chr12104879947104880042E074-11355
chr12104880120104880613E074-10784
chr12104880678104881066E074-10331
chr12104887127104887278E074-4119
chr12104887447104887631E074-3766
chr12104900424104901172E0749027
chr12104903920104904022E07412523
chr12104904031104904421E07412634
chr12104904473104904575E07413076
chr12104912778104913952E07421381
chr12104915091104915151E07423694
chr12104915236104915446E07423839
chr12104915493104915769E07424096
chr12104917853104918187E07426456
chr12104918484104918609E07427087
chr12104845746104845806E081-45591
chr12104845811104845865E081-45532
chr12104846017104846251E081-45146
chr12104846394104846507E081-44890
chr12104879368104879915E081-11482
chr12104879947104880042E081-11355
chr12104880120104880613E081-10784
chr12104880678104881066E081-10331
chr12104881084104881548E081-9849
chr12104899095104899180E0817698
chr12104900424104901172E0819027
chr12104901192104901242E0819795
chr12104901346104901717E0819949
chr12104901724104901827E08110327
chr12104901831104901888E08110434
chr12104916823104917796E08125426
chr12104917853104918187E08126456
chr12104918484104918609E08127087
chr12104927997104928560E08136600
chr12104928665104928733E08137268
chr12104928771104928877E08137374
chr12104928950104929054E08137553
chr12104929203104929432E08137806
chr12104862581104862621E082-28776
chr12104862659104862734E082-28663
chr12104862788104862916E082-28481
chr12104862938104863072E082-28325
chr12104863143104863584E082-27813
chr12104867133104867815E082-23582
chr12104879368104879915E082-11482
chr12104879947104880042E082-11355
chr12104880678104881066E082-10331
chr12104881084104881548E082-9849
chr12104899619104899681E0828222
chr12104899729104899789E0828332
chr12104900076104900161E0828679
chr12104900424104901172E0829027
chr12104901192104901242E0829795
chr12104901346104901717E0829949
chr12104901724104901827E08210327
chr12104903920104904022E08212523
chr12104904031104904421E08212634
chr12104904473104904575E08213076
chr12104907394104907865E08215997
chr12104907925104908091E08216528
chr12104912778104913952E08221381
chr12104915493104915769E08224096
chr12104916071104916121E08224674
chr12104916823104917796E08225426
chr12104917853104918187E08226456










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr12104849658104853772E067-37625
chr12104849658104853772E068-37625
chr12104849658104853772E069-37625
chr12104849658104853772E070-37625
chr12104849658104853772E071-37625
chr12104849658104853772E072-37625
chr12104849658104853772E073-37625
chr12104849658104853772E074-37625
chr12104849658104853772E081-37625
chr12104849658104853772E082-37625