rs1111644

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
T==0196 (5872/29934,GnomAD)
T==0183 (5339/29118,TOPMED)
T==0150 (749/5008,1000G)
T==0253 (976/3854,ALSPAC)
T==0252 (933/3708,TWINSUK)
chr7:10412949 (GRCh38.p7) (7p21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
24 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.10412949T>G
GRCh37.p13 chr 7NC_000007.13:g.10452576T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.104G=0.896
1000GenomesAmericanSub694T=0.280G=0.720
1000GenomesEast AsianSub1008T=0.054G=0.946
1000GenomesEuropeSub1006T=0.236G=0.764
1000GenomesGlobalStudy-wide5008T=0.150G=0.850
1000GenomesSouth AsianSub978T=0.130G=0.870
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.253G=0.747
The Genome Aggregation DatabaseAfricanSub8724T=0.121G=0.879
The Genome Aggregation DatabaseAmericanSub836T=0.280G=0.720
The Genome Aggregation DatabaseEast AsianSub1616T=0.033G=0.967
The Genome Aggregation DatabaseEuropeSub18456T=0.241G=0.758
The Genome Aggregation DatabaseGlobalStudy-wide29934T=0.196G=0.803
The Genome Aggregation DatabaseOtherSub302T=0.240G=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.183G=0.816
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.252G=0.748
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs11116442.8E-05alcoholism (heaviness of drinking)21529783

eQTL of rs1111644 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1111644 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr71046881410468874E06916238
chr71046896210469097E06916386
chr71046920110469556E06916625
chr71046975510469883E06917179
chr71047002210470072E06917446
chr71046834710468446E07015771
chr71046868210468722E07016106
chr71046881410468874E07016238
chr71046896210469097E07016386
chr71046920110469556E07016625
chr71046975510469883E07017179
chr71046834710468446E07115771
chr71046868210468722E07116106
chr71046881410468874E07116238
chr71046896210469097E07116386
chr71046920110469556E07116625
chr71046975510469883E07117179
chr71047002210470072E07117446
chr71046920110469556E07216625
chr71046881410468874E07416238
chr71046896210469097E07416386
chr71046920110469556E07416625
chr71046975510469883E07417179
chr71047002210470072E07417446