rs11118748

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0052 (1557/29970,GnomAD)
T=0062 (1828/29116,TOPMED)
T=0072 (362/5008,1000G)
T=0023 (88/3854,ALSPAC)
T=0028 (103/3708,TWINSUK)
chr1:221541794 (GRCh38.p7) (1q41)
ND
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.221541794C>T
GRCh37.p13 chr 1NC_000001.10:g.221715136C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.849T=0.151
1000GenomesAmericanSub694C=0.960T=0.040
1000GenomesEast AsianSub1008C=0.948T=0.052
1000GenomesEuropeSub1006C=0.969T=0.031
1000GenomesGlobalStudy-wide5008C=0.928T=0.072
1000GenomesSouth AsianSub978C=0.950T=0.050
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.977T=0.023
The Genome Aggregation DatabaseAfricanSub8714C=0.887T=0.113
The Genome Aggregation DatabaseAmericanSub838C=0.970T=0.030
The Genome Aggregation DatabaseEast AsianSub1618C=0.950T=0.050
The Genome Aggregation DatabaseEuropeSub18498C=0.975T=0.024
The Genome Aggregation DatabaseGlobalStudy-wide29970C=0.948T=0.052
The Genome Aggregation DatabaseOtherSub302C=0.960T=0.040
Trans-Omics for Precision MedicineGlobalStudy-wide29116C=0.937T=0.062
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.972T=0.028
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs111187481.84E-05alcohol and nictotine co-dependence20158304

eQTL of rs11118748 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11118748 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1221717151221717292E0682015
chr1221717151221717292E0722015