rs11126651

Homo sapiens
T>G
LOC101927967 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0205 (6156/29952,GnomAD)
G=0191 (5581/29116,TOPMED)
G=0172 (863/5008,1000G)
G=0242 (932/3854,ALSPAC)
G=0238 (881/3708,TWINSUK)
chr2:78077669 (GRCh38.p7) (2p12)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.78077669T>G
GRCh37.p13 chr 2NC_000002.11:g.78304795T>G

Gene: LOC101927967, uncharacterized LOC101927967(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC101927967 transcriptNR_110288.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.819G=0.181
1000GenomesAmericanSub694T=0.850G=0.150
1000GenomesEast AsianSub1008T=0.880G=0.120
1000GenomesEuropeSub1006T=0.812G=0.188
1000GenomesGlobalStudy-wide5008T=0.828G=0.172
1000GenomesSouth AsianSub978T=0.790G=0.210
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.758G=0.242
The Genome Aggregation DatabaseAfricanSub8714T=0.800G=0.200
The Genome Aggregation DatabaseAmericanSub838T=0.830G=0.170
The Genome Aggregation DatabaseEast AsianSub1622T=0.883G=0.117
The Genome Aggregation DatabaseEuropeSub18476T=0.782G=0.217
The Genome Aggregation DatabaseGlobalStudy-wide29952T=0.794G=0.205
The Genome Aggregation DatabaseOtherSub302T=0.810G=0.190
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.808G=0.191
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.762G=0.238
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs111266510.00027Alcohol dependence (early age of onset)20201924
rs111266510.00088alcohol dependence20201924

eQTL of rs11126651 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11126651 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr27835439078354522E06849595
chr27830482978305092E06934
chr27830535778305485E069562
chr27835439078354522E07149595