rs1112787

Homo sapiens
C>T
ADARB2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0239 (7183/29968,GnomAD)
T=0258 (7524/29118,TOPMED)
T=0210 (1050/5008,1000G)
T=0267 (1029/3854,ALSPAC)
T=0270 (1003/3708,TWINSUK)
chr10:1604704 (GRCh38.p7) (10p15.3)
AD
GWASdb2
1   publication(s)
See rs on genome
108 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.1604704C>T
GRCh37.p13 chr 10NC_000010.10:g.1646899C>T

Gene: ADARB2, adenosine deaminase, RNA specific B2 (inactive)(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ADARB2 transcriptNM_018702.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.794T=0.206
1000GenomesAmericanSub694C=0.800T=0.200
1000GenomesEast AsianSub1008C=0.809T=0.191
1000GenomesEuropeSub1006C=0.733T=0.267
1000GenomesGlobalStudy-wide5008C=0.790T=0.210
1000GenomesSouth AsianSub978C=0.820T=0.180
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.733T=0.267
The Genome Aggregation DatabaseAfricanSub8720C=0.783T=0.217
The Genome Aggregation DatabaseAmericanSub836C=0.800T=0.200
The Genome Aggregation DatabaseEast AsianSub1616C=0.816T=0.184
The Genome Aggregation DatabaseEuropeSub18494C=0.743T=0.256
The Genome Aggregation DatabaseGlobalStudy-wide29968C=0.760T=0.239
The Genome Aggregation DatabaseOtherSub302C=0.720T=0.280
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.741T=0.258
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.730T=0.270
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs11127870.00097alcohol dependence20201924

eQTL of rs1112787 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1112787 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1016873691687456E06740470
chr1016877841687867E06740885
chr1016881061688156E06741207
chr1016888701688949E06741971
chr1016890611689111E06742162
chr1016011801601242E068-45657
chr1016012571601396E068-45503
chr1016014611601527E068-45372
chr1016015441601623E068-45276
chr1016137481614109E068-32790
chr1016141261614226E068-32673
chr1016506141650685E0683715
chr1016888701688949E06841971
chr1016890611689111E06842162
chr1016011801601242E069-45657
chr1016012571601396E069-45503
chr1016014611601527E069-45372
chr1016137481614109E069-32790
chr1016141261614226E069-32673
chr1016877841687867E06940885
chr1016881061688156E06941207
chr1016888701688949E06941971
chr1016890611689111E06942162
chr1016893511689401E06942452
chr1016935951693649E06946696
chr1016944201694786E06947521
chr1016948181694923E06947919
chr1016949811695041E06948082
chr1016390591639150E070-7749
chr1016504761650569E0703577
chr1016506141650685E0703715
chr1016516841652015E0704785
chr1016520371652181E0705138
chr1016525311652581E0705632
chr1016792711679517E07032372
chr1016796051679722E07032706
chr1016798451679895E07032946
chr1016799491680042E07033050
chr1016810531681279E07034154
chr1016859681686107E07039069
chr1016862421686322E07039343
chr1016931591693462E07046260
chr1016935951693649E07046696
chr1016937321693846E07046833
chr1016940211694074E07047122
chr1016941701694230E07047271
chr1016942941694369E07047395
chr1016137481614109E071-32790
chr1016141261614226E071-32673
chr1016506141650685E0713715
chr1016516841652015E0714785
chr1016873691687456E07140470
chr1016881061688156E07141207
chr1016137481614109E072-32790
chr1016141261614226E072-32673
chr1016144981615098E072-31801
chr1016873691687456E07240470
chr1016877841687867E07240885
chr1016881061688156E07241207
chr1016137481614109E073-32790
chr1016141261614226E073-32673
chr1016506141650685E0733715
chr1016862421686322E07339343
chr1016137481614109E074-32790
chr1016141261614226E074-32673
chr1016429201643444E074-3455
chr1016506141650685E0743715
chr1016881061688156E07441207
chr1016888701688949E07441971
chr1016890611689111E07442162
chr1016177131617777E081-29122
chr1016201581620219E081-26680
chr1016203321620494E081-26405
chr1016208061620856E081-26043
chr1016335991633680E081-13219
chr1016338421633936E081-12963
chr1016372321637379E081-9520
chr1016506141650685E0813715
chr1016516841652015E0814785
chr1016520371652181E0815138
chr1016744471674515E08127548
chr1016745611674615E08127662
chr1016859681686107E08139069
chr1016862421686322E08139343
chr1016873691687456E08140470
chr1016895991689649E08142700
chr1016935951693649E08146696
chr1016937321693846E08146833
chr1016940211694074E08147122
chr1016941701694230E08147271
chr1016942941694369E08147395
chr1016944201694786E08147521
chr1016172021617311E082-29588
chr1016174901617648E082-29251
chr1016177131617777E082-29122
chr1016435891643938E082-2961
chr1016504761650569E0823577
chr1016506141650685E0823715
chr1016516841652015E0824785
chr1016520371652181E0825138
chr1016859681686107E08239069
chr1016862421686322E08239343
chr1016940211694074E08247122
chr1016941701694230E08247271
chr1016942941694369E08247395
chr1016944201694786E08247521
chr1016948181694923E08247919
chr1016949811695041E08248082