rs11129574

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0079 (2372/29962,GnomAD)
T=0059 (1720/29118,TOPMED)
T=0127 (635/5008,1000G)
T=0074 (285/3854,ALSPAC)
T=0066 (244/3708,TWINSUK)
chr3:33972800 (GRCh38.p7) (3p22.3)
AD
GWASCatalog
1   publication(s)
See rs on genome
30 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.33972800C>T
GRCh37.p13 chr 3NC_000003.11:g.34014292C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.983T=0.017
1000GenomesAmericanSub694C=0.860T=0.140
1000GenomesEast AsianSub1008C=0.761T=0.239
1000GenomesEuropeSub1006C=0.922T=0.078
1000GenomesGlobalStudy-wide5008C=0.873T=0.127
1000GenomesSouth AsianSub978C=0.800T=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.926T=0.074
The Genome Aggregation DatabaseAfricanSub8720C=0.971T=0.029
The Genome Aggregation DatabaseAmericanSub838C=0.850T=0.150
The Genome Aggregation DatabaseEast AsianSub1614C=0.746T=0.254
The Genome Aggregation DatabaseEuropeSub18488C=0.916T=0.084
The Genome Aggregation DatabaseGlobalStudy-wide29962C=0.920T=0.079
The Genome Aggregation DatabaseOtherSub302C=0.920T=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.940T=0.059
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.934T=0.066
PMID Title Author Journal
29071344Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.Zhou HJAMA Psychiatry

P-Value

SNP ID p-value Traits Study
rs111295744E-06alcohol dependence29071344

eQTL of rs11129574 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11129574 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr33397867133979241E070-35051
chr33397928233979407E070-34885
chr33397957233979711E070-34581
chr33398239633982501E070-31791
chr33398265433982712E070-31580
chr33398348133983532E070-30760
chr33398414733984311E070-29981
chr33398441633984542E070-29750
chr33398414733984311E071-29981
chr33398441633984542E071-29750
chr33405322134053339E08138929
chr33405339334053916E08139101
chr33405484534055044E08140553
chr33405548834056234E08141196
chr33405705634057268E08142764
chr33405738934057509E08143097
chr33405756334057617E08143271
chr33405822434058336E08143932
chr33405837134058973E08144079
chr33406208734062137E08147795
chr33406219134062455E08147899
chr33406374834063871E08149456
chr33397848833978607E082-35685
chr33397867133979241E082-35051
chr33405484534055044E08240553
chr33405548834056234E08241196
chr33405837134058973E08244079
chr33406208734062137E08247795
chr33406219134062455E08247899
chr33406374834063871E08249456