rs1113371

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
A==0492 (14684/29848,GnomAD)
A==0467 (13600/29118,TOPMED)
A==0488 (2443/5008,1000G)
C=0490 (1887/3854,ALSPAC)
A==0500 (1854/3708,TWINSUK)
C=0500 (1854/3708,TWINSUK)
chr4:35460417 (GRCh38.p7) (4p15.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
4 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.35460417A>C
GRCh37.p13 chr 4NC_000004.11:g.35462039A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.401C=0.599
1000GenomesAmericanSub694A=0.450C=0.550
1000GenomesEast AsianSub1008A=0.643C=0.357
1000GenomesEuropeSub1006A=0.538C=0.462
1000GenomesGlobalStudy-wide5008A=0.488C=0.512
1000GenomesSouth AsianSub978A=0.420C=0.580
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.510C=0.490
The Genome Aggregation DatabaseAfricanSub8700A=0.429C=0.571
The Genome Aggregation DatabaseAmericanSub836A=0.420C=0.580
The Genome Aggregation DatabaseEast AsianSub1610A=0.676C=0.324
The Genome Aggregation DatabaseEuropeSub18402A=0.507C=0.492
The Genome Aggregation DatabaseGlobalStudy-wide29848A=0.492C=0.508
The Genome Aggregation DatabaseOtherSub300A=0.580C=0.420
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.467C=0.532
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.500C=0.500
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs11133710.000451nicotine dependence17158188

eQTL of rs1113371 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1113371 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr43546529835465454E0693259
chr43546529835465454E0713259
chr43546529835465454E0743259



Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr43546683035466880E0674791
chr43546683035466880E0694791
chr43546683035466880E0714791
chr43546683035466880E0724791