SNP Detail Info-rs11151527

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

DOK6 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0417 (12468/29882,GnomAD)
A==0447 (13031/29118,TOPMED)
A==0435 (2176/5008,1000G)
A==0348 (1342/3854,ALSPAC)
A==0353 (1309/3708,TWINSUK)

Position: chr18:69679897 (GRCh38.p7) (18q22.2)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 11 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 18	NC_000018.10:g.69679897A>G
GRCh37.p13 chr 18	NC_000018.9:g.67347133A>G

Molecule type	Change	Amino acid[Codon]	SO Term
DOK6 transcript	NM_152721.5:c.	N/A	Intron Variant
DOK6 transcript variant X1	XM_011525875.2:c.	N/A	Intron Variant
DOK6 transcript variant X2	XM_017025610.1:c.	N/A	Intron Variant
DOK6 transcript variant X3	XM_017025611.1:c.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.573	G=0.427
1000Genomes	American	Sub	694	A=0.540	G=0.460
1000Genomes	East Asian	Sub	1008	A=0.216	G=0.784
1000Genomes	Europe	Sub	1006	A=0.359	G=0.641
1000Genomes	Global	Study-wide	5008	A=0.435	G=0.565
1000Genomes	South Asian	Sub	978	A=0.470	G=0.530
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.348	G=0.652
The Genome Aggregation Database	African	Sub	8692	A=0.529	G=0.471
The Genome Aggregation Database	American	Sub	834	A=0.530	G=0.470
The Genome Aggregation Database	East Asian	Sub	1616	A=0.187	G=0.813
The Genome Aggregation Database	Europe	Sub	18438	A=0.379	G=0.620
The Genome Aggregation Database	Global	Study-wide	29882	A=0.417	G=0.582
The Genome Aggregation Database	Other	Sub	302	A=0.410	G=0.590
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.447	G=0.552
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.353	G=0.647

PMID	Title	Author	Journal
19268276	Genome-wide association study of smoking initiation and current smoking.	Vink JM	Am J Hum Genet

SNP ID	p-value	Traits	Study
rs11151527	0.000265	nicotine smoking	19268276

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr18	67341810	67341899	E067	-5234
chr18	67341944	67342128	E067	-5005
chr18	67297192	67297242	E070	-49891
chr18	67341810	67341899	E074	-5234
chr18	67341944	67342128	E074	-5005
chr18	67342152	67342235	E074	-4898
chr18	67297192	67297242	E081	-49891
chr18	67341810	67341899	E081	-5234
chr18	67341944	67342128	E081	-5005
chr18	67396863	67397028	E081	49730
chr18	67297667	67298261	E082	-48872

rs11151527