SNP Detail Info-rs11157219

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0227 (6789/29914,GnomAD)
G=0214 (6240/29118,TOPMED)
G=0208 (1042/5008,1000G)
G=0282 (1087/3854,ALSPAC)
G=0282 (1047/3708,TWINSUK)

Position: chr14:41313498 (GRCh38.p7) (14q21.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 14	NC_000014.9:g.41313498A>G
GRCh37.p13 chr 14	NC_000014.8:g.41782701A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.887	G=0.113
1000Genomes	American	Sub	694	A=0.790	G=0.210
1000Genomes	East Asian	Sub	1008	A=0.834	G=0.166
1000Genomes	Europe	Sub	1006	A=0.743	G=0.257
1000Genomes	Global	Study-wide	5008	A=0.792	G=0.208
1000Genomes	South Asian	Sub	978	A=0.670	G=0.330
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.718	G=0.282
The Genome Aggregation Database	African	Sub	8714	A=0.831	G=0.169
The Genome Aggregation Database	American	Sub	836	A=0.830	G=0.170
The Genome Aggregation Database	East Asian	Sub	1610	A=0.807	G=0.193
The Genome Aggregation Database	Europe	Sub	18452	A=0.740	G=0.259
The Genome Aggregation Database	Global	Study-wide	29914	A=0.773	G=0.227
The Genome Aggregation Database	Other	Sub	302	A=0.750	G=0.250
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.785	G=0.214
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.718	G=0.282

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs11157219	8.78E-05	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr14	41754505	41754720	E070	-27981
chr14	41747200	41747372	E081	-35329
chr14	41747200	41747372	E082	-35329

rs11157219