rs11163319

Homo sapiens
A>C
ADGRL2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0285 (1425/5008,1000G)
C=0016 (61/3854,ALSPAC)
C=0015 (55/3708,TWINSUK)
chr1:81506757 (GRCh38.p7) (1p31.1)
OD
GWASCatalog
1   publication(s)
See rs on genome
35 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.81506757A>C
GRCh37.p13 chr 1NC_000001.10:g.81972442A>C

Gene: ADGRL2, adhesion G protein-coupled receptor L2(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ADGRL2 transcript variant 2NM_001297704.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant 3NM_001297705.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant 4NM_001297706.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant 1NM_012302.3:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X2XM_017000782.1:c.N/AIntron Variant
ADGRL2 transcript variant X7XM_005270666.4:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X10XM_005270668.2:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X1XM_006710485.3:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X2XM_006710488.2:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X4XM_006710489.3:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X3XM_017000783.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X3XM_017000784.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X7XM_017000785.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X6XM_017000786.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X9XM_017000787.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X11XM_017000788.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X12XM_017000789.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X14XM_017000790.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X15XM_017000791.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X16XM_017000792.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X20XM_017000793.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X23XM_017000794.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X24XM_017000795.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X14XM_017000796.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X26XM_017000797.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X27XM_017000798.1:c.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X17XR_001737067.1:n.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X18XR_001737068.1:n.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X19XR_001737069.1:n.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X21XR_001737070.1:n.N/AGenic Upstream Transcript Variant
ADGRL2 transcript variant X22XR_001737071.1:n.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.462C=0.538
1000GenomesAmericanSub694A=0.830C=0.170
1000GenomesEast AsianSub1008A=0.699C=0.301
1000GenomesEuropeSub1006A=0.924C=0.076
1000GenomesGlobalStudy-wide5008A=0.715C=0.285
1000GenomesSouth AsianSub978A=0.780C=0.220
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.984C=0.016
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.985C=0.015
PMID Title Author Journal
29478698Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans.Cheng ZBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs111633191E-06Opioid dependence29478698

eQTL of rs11163319 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11163319 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr18193030981930353E070-42089
chr18193044881930505E070-41937
chr18193313381933479E070-38963
chr18193584981935909E070-36533
chr18196416181964267E070-8175
chr18196436081964463E070-7979
chr18196449981964734E070-7708
chr18196474681964832E070-7610
chr18196491381965072E070-7370
chr18197486181974931E0702419
chr18197514181975757E0702699
chr18197832481978399E0705882
chr18197847681978558E0706034
chr18193030981930353E081-42089
chr18193044881930505E081-41937
chr18193279281932937E081-39505
chr18193313381933479E081-38963
chr18195912281959894E081-12548
chr18196020081960324E081-12118
chr18196068581960959E081-11483
chr18196190181962508E081-9934
chr18196269081962748E081-9694
chr18196281781962881E081-9561
chr18197514181975757E0812699
chr18197694681977048E0814504
chr18197712481977237E0814682
chr18193030981930353E082-42089
chr18193279281932937E082-39505
chr18193313381933479E082-38963
chr18196020081960324E082-12118
chr18196068581960959E082-11483
chr18197784681977939E0825404
chr18197797881978260E0825536
chr18197832481978399E0825882
chr18197847681978558E0826034