rs11167764

Homo sapiens
A>C
LOC105378204 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0200 (6011/29952,GnomAD)
A==0207 (6045/29118,TOPMED)
A==0189 (946/5008,1000G)
A==0224 (864/3854,ALSPAC)
A==0214 (794/3708,TWINSUK)
chr5:142099500 (GRCh38.p7) (5q31.3)
AD
GWASdb2
5   publication(s)
See rs on genome
184 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.142099500A>C
GRCh37.p13 chr 5NC_000005.9:g.141479065A>C

Gene: LOC105378204, uncharacterized LOC105378204(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105378204 transcriptXR_944368.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.194C=0.806
1000GenomesAmericanSub694A=0.170C=0.830
1000GenomesEast AsianSub1008A=0.166C=0.834
1000GenomesEuropeSub1006A=0.210C=0.790
1000GenomesGlobalStudy-wide5008A=0.189C=0.811
1000GenomesSouth AsianSub978A=0.200C=0.800
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.224C=0.776
The Genome Aggregation DatabaseAfricanSub8718A=0.207C=0.793
The Genome Aggregation DatabaseAmericanSub836A=0.170C=0.830
The Genome Aggregation DatabaseEast AsianSub1620A=0.149C=0.851
The Genome Aggregation DatabaseEuropeSub18478A=0.204C=0.795
The Genome Aggregation DatabaseGlobalStudy-wide29952A=0.200C=0.799
The Genome Aggregation DatabaseOtherSub300A=0.140C=0.860
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.207C=0.792
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.214C=0.786
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res
21907864Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.Ferreira MALancet
22544929IRF5 risk polymorphisms contribute to interindividual variance in pattern recognition receptor-mediated cytokine secretion in human monocyte-derived cells.Hedl MJ Immunol
26103568Association Study of IL-12B Polymorphisms Susceptibility with Ankylosing Spondylitis in Mainland Han Population.Zhang LPLoS One
21102463Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.Franke ANat Genet

P-Value

SNP ID p-value Traits Study
rs111677640.00024alcohol dependence20201924

eQTL of rs11167764 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11167764 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5141432687141432843E067-46222
chr5141432931141433953E067-45112
chr5141436389141436578E067-42487
chr5141436625141436772E067-42293
chr5141437020141437094E067-41971
chr5141439025141439101E067-39964
chr5141439173141439403E067-39662
chr5141443042141444398E067-34667
chr5141444944141445180E067-33885
chr5141445870141445960E067-33105
chr5141446082141446272E067-32793
chr5141487642141487707E0678577
chr5141500239141500327E06721174
chr5141500451141500501E06721386
chr5141507676141507760E06728611
chr5141508433141508671E06729368
chr5141524844141525300E06745779
chr5141525374141525437E06746309
chr5141432687141432843E068-46222
chr5141432931141433953E068-45112
chr5141436625141436772E068-42293
chr5141437020141437094E068-41971
chr5141437225141437634E068-41431
chr5141437640141437819E068-41246
chr5141439025141439101E068-39964
chr5141439173141439403E068-39662
chr5141444944141445180E068-33885
chr5141458891141459383E068-19682
chr5141459914141460023E068-19042
chr5141494472141494553E06815407
chr5141495582141495765E06816517
chr5141495983141496059E06816918
chr5141508433141508671E06829368
chr5141508902141508952E06829837
chr5141524844141525300E06845779
chr5141525374141525437E06846309
chr5141432687141432843E069-46222
chr5141432931141433953E069-45112
chr5141434150141434323E069-44742
chr5141436625141436772E069-42293
chr5141437020141437094E069-41971
chr5141437225141437634E069-41431
chr5141438810141438864E069-40201
chr5141439025141439101E069-39964
chr5141439173141439403E069-39662
chr5141442182141442361E069-36704
chr5141445870141445960E069-33105
chr5141446082141446272E069-32793
chr5141487642141487707E0698577
chr5141492438141492491E06913373
chr5141492653141492760E06913588
chr5141494472141494553E06915407
chr5141497314141497741E06918249
chr5141499989141500071E06920924
chr5141500239141500327E06921174
chr5141500451141500501E06921386
chr5141501853141501920E06922788
chr5141507676141507760E06928611
chr5141508902141508952E06929837
chr5141524844141525300E06945779
chr5141432931141433953E070-45112
chr5141434150141434323E070-44742
chr5141436389141436578E070-42487
chr5141436625141436772E070-42293
chr5141437020141437094E070-41971
chr5141442182141442361E070-36704
chr5141444944141445180E070-33885
chr5141445870141445960E070-33105
chr5141446082141446272E070-32793
chr5141457914141458108E070-20957
chr5141458197141458281E070-20784
chr5141458891141459383E070-19682
chr5141459546141459596E070-19469
chr5141459848141459900E070-19165
chr5141459914141460023E070-19042
chr5141500451141500501E07021386
chr5141432687141432843E071-46222
chr5141432931141433953E071-45112
chr5141434150141434323E071-44742
chr5141436389141436578E071-42487
chr5141436625141436772E071-42293
chr5141437020141437094E071-41971
chr5141437225141437634E071-41431
chr5141437640141437819E071-41246
chr5141437877141438121E071-40944
chr5141439173141439403E071-39662
chr5141442182141442361E071-36704
chr5141444944141445180E071-33885
chr5141487642141487707E0718577
chr5141495582141495765E07116517
chr5141497314141497741E07118249
chr5141497905141497989E07118840
chr5141498114141498323E07119049
chr5141500239141500327E07121174
chr5141500451141500501E07121386
chr5141501853141501920E07122788
chr5141506900141507129E07127835
chr5141507676141507760E07128611
chr5141508433141508671E07129368
chr5141432931141433953E072-45112
chr5141434150141434323E072-44742
chr5141436389141436578E072-42487
chr5141436625141436772E072-42293
chr5141437020141437094E072-41971
chr5141437225141437634E072-41431
chr5141437640141437819E072-41246
chr5141439025141439101E072-39964
chr5141439173141439403E072-39662
chr5141442182141442361E072-36704
chr5141445870141445960E072-33105
chr5141446082141446272E072-32793
chr5141487642141487707E0728577
chr5141495582141495765E07216517
chr5141497905141497989E07218840
chr5141498114141498323E07219049
chr5141498690141498908E07219625
chr5141506900141507129E07227835
chr5141507676141507760E07228611
chr5141508902141508952E07229837
chr5141432687141432843E073-46222
chr5141432931141433953E073-45112
chr5141436625141436772E073-42293
chr5141437020141437094E073-41971
chr5141437225141437634E073-41431
chr5141437640141437819E073-41246
chr5141445870141445960E073-33105
chr5141446082141446272E073-32793
chr5141494472141494553E07315407
chr5141495582141495765E07316517
chr5141495983141496059E07316918
chr5141498114141498323E07319049
chr5141498690141498908E07319625
chr5141500239141500327E07321174
chr5141500451141500501E07321386
chr5141506900141507129E07327835
chr5141507676141507760E07328611
chr5141508902141508952E07329837
chr5141432687141432843E074-46222
chr5141432931141433953E074-45112
chr5141436389141436578E074-42487
chr5141436625141436772E074-42293
chr5141437020141437094E074-41971
chr5141437225141437634E074-41431
chr5141437640141437819E074-41246
chr5141437877141438121E074-40944
chr5141443042141444398E074-34667
chr5141444944141445180E074-33885
chr5141487642141487707E0748577
chr5141494472141494553E07415407
chr5141497314141497741E07418249
chr5141497905141497989E07418840
chr5141498114141498323E07419049
chr5141498690141498908E07419625
chr5141506900141507129E07427835
chr5141507676141507760E07428611
chr5141508433141508671E07429368
chr5141508902141508952E07429837
chr5141525374141525437E07446309
chr5141525797141525946E07446732
chr5141432931141433953E081-45112
chr5141436389141436578E081-42487
chr5141436625141436772E081-42293
chr5141437020141437094E081-41971
chr5141443042141444398E081-34667
chr5141444944141445180E081-33885
chr5141445870141445960E081-33105
chr5141446082141446272E081-32793
chr5141458197141458281E081-20784
chr5141458891141459383E081-19682
chr5141486750141486865E0817685
chr5141487055141487620E0817990
chr5141487642141487707E0818577
chr5141432931141433953E082-45112
chr5141436389141436578E082-42487
chr5141436625141436772E082-42293
chr5141437020141437094E082-41971
chr5141437225141437634E082-41431
chr5141437640141437819E082-41246
chr5141437877141438121E082-40944
chr5141444944141445180E082-33885
chr5141445870141445960E082-33105
chr5141446082141446272E082-32793
chr5141487055141487620E0827990
chr5141507676141507760E08228611










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr5141487834141490107E0678769
chr5141487834141490107E0688769
chr5141487834141490107E0698769
chr5141487834141490107E0708769
chr5141487834141490107E0718769
chr5141487834141490107E0728769
chr5141487834141490107E0738769
chr5141487834141490107E0748769
chr5141487834141490107E0818769
chr5141487834141490107E0828769