rs11170792

Homo sapiens
G>A
FLJ12825 : 2KB Upstream Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0200 (5988/29940,GnomAD)
A=0192 (5615/29118,TOPMED)
A=0196 (981/5008,1000G)
A=0204 (785/3854,ALSPAC)
A=0204 (758/3708,TWINSUK)
chr12:54057092 (GRCh38.p7) (12q13.13)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
5 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.54057092G>A
GRCh37.p13 chr 12NC_000012.11:g.54450876G>A
HOXC4/HOXC5/HOXC6 RefSeqGeneNG_029818.1:g.45235G>A

Gene: FLJ12825, uncharacterized LOC440101(plus strand): 2KB Upstream Variant

Molecule type Change Amino acid[Codon] SO Term
FLJ12825 transcriptNR_026655.1:n.N/AUpstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.827A=0.173
1000GenomesAmericanSub694G=0.870A=0.130
1000GenomesEast AsianSub1008G=0.830A=0.170
1000GenomesEuropeSub1006G=0.798A=0.202
1000GenomesGlobalStudy-wide5008G=0.804A=0.196
1000GenomesSouth AsianSub978G=0.700A=0.300
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.796A=0.204
The Genome Aggregation DatabaseAfricanSub8712G=0.834A=0.166
The Genome Aggregation DatabaseAmericanSub836G=0.860A=0.140
The Genome Aggregation DatabaseEast AsianSub1618G=0.858A=0.142
The Genome Aggregation DatabaseEuropeSub18472G=0.777A=0.222
The Genome Aggregation DatabaseGlobalStudy-wide29940G=0.800A=0.200
The Genome Aggregation DatabaseOtherSub302G=0.670A=0.330
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.807A=0.192
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.796A=0.204
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs111707920.0007alcohol dependence20201924

eQTL of rs11170792 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11170792 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr125450071154500870E06849835
chr125450071154500870E07149835
chr125450071154500870E08149835



Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr125447491554475234E07124039
chr125447536554475432E07124489
chr125447548554475811E07124609
chr125447585554475953E07124979
chr125447601854476387E07125142