rs11188984

Homo sapiens
C>T
SLIT1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0024 (2721/108866,ExAC)
T=0014 (442/29990,GnomAD)
T=0012 (349/29118,TOPMED)
C==0005 (77/13006,GO-ESP)
T=0038 (192/5008,1000G)
T=0005 (18/3854,ALSPAC)
T=0005 (17/3708,TWINSUK)
chr10:97006464 (GRCh38.p7) (10q24.1)
AD
GWASdb2
1   publication(s)
See rs on genome
105 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.97006464C>T
GRCh37.p13 chr 10NC_000010.10:g.98766221C>T

Gene: SLIT1, slit guidance ligand 1(minus strand)

Molecule type Change Amino acid[Codon] SO Term
SLIT1 transcriptNM_003061.2:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.994T=0.006
1000GenomesAmericanSub694C=1.000T=0.000
1000GenomesEast AsianSub1008C=0.909T=0.091
1000GenomesEuropeSub1006C=0.991T=0.009
1000GenomesGlobalStudy-wide5008C=0.962T=0.038
1000GenomesSouth AsianSub978C=0.920T=0.080
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.995T=0.005
The Exome Aggregation ConsortiumAmericanSub19600C=0.994T=0.005
The Exome Aggregation ConsortiumAsianSub22482C=0.915T=0.084
The Exome Aggregation ConsortiumEuropeSub65984C=0.989T=0.010
The Exome Aggregation ConsortiumGlobalStudy-wide108866C=0.975T=0.024
The Exome Aggregation ConsortiumOtherSub800C=0.960T=0.040
The Genome Aggregation DatabaseAfricanSub8734C=0.994T=0.006
The Genome Aggregation DatabaseAmericanSub838C=0.990T=0.010
The Genome Aggregation DatabaseEast AsianSub1618C=0.912T=0.088
The Genome Aggregation DatabaseEuropeSub18498C=0.987T=0.012
The Genome Aggregation DatabaseGlobalStudy-wide29990C=0.985T=0.014
The Genome Aggregation DatabaseOtherSub302C=0.970T=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.988T=0.012
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.995T=0.005
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs111889840.00032alcohol dependence20201924

eQTL of rs11188984 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11188984 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr109872275898722836E067-43385
chr109872301698723119E067-43102
chr109875544898756496E067-9725
chr109878024098781081E06714019
chr109878116098781289E06714939
chr109878140598781455E06715184
chr109878166998781843E06715448
chr109878191698781960E06715695
chr109878521698785793E06718995
chr109874596398746181E068-20040
chr109874633298746490E068-19731
chr109875544898756496E068-9725
chr109875655098756600E068-9621
chr109878024098781081E06814019
chr109878116098781289E06814939
chr109874596398746181E069-20040
chr109874633298746490E069-19731
chr109875544898756496E069-9725
chr109877997398780106E06913752
chr109878024098781081E06914019
chr109878116098781289E06914939
chr109878140598781455E06915184
chr109878166998781843E06915448
chr109878191698781960E06915695
chr109878521698785793E06918995
chr109879817798798257E06931956
chr109874386298745376E070-20845
chr109874596398746181E070-20040
chr109874633298746490E070-19731
chr109874659298746676E070-19545
chr109874689698746946E070-19275
chr109874792298748597E070-17624
chr109878024098781081E07014019
chr109878116098781289E07014939
chr109879329898793364E07027077
chr109879817798798257E07031956
chr109879835398798446E07032132
chr109879884398798941E07032622
chr109881280998812864E07046588
chr109881301298813299E07046791
chr109881349198813567E07047270
chr109872301698723119E071-43102
chr109872315398723443E071-42778
chr109874596398746181E071-20040
chr109874633298746490E071-19731
chr109875248198752978E071-13243
chr109878024098781081E07114019
chr109878116098781289E07114939
chr109878140598781455E07115184
chr109878166998781843E07115448
chr109878191698781960E07115695
chr109878521698785793E07118995
chr109879817798798257E07131956
chr109871958198719667E072-46554
chr109871971498719976E072-46245
chr109872002098720075E072-46146
chr109872056898720636E072-45585
chr109872076698720838E072-45383
chr109874596398746181E072-20040
chr109874633298746490E072-19731
chr109875493998755187E072-11034
chr109875544898756496E072-9725
chr109875655098756600E072-9621
chr109877700198777304E07210780
chr109878024098781081E07214019
chr109878116098781289E07214939
chr109878166998781843E07215448
chr109878191698781960E07215695
chr109878521698785793E07218995
chr109879817798798257E07231956
chr109874596398746181E073-20040
chr109875544898756496E073-9725
chr109878024098781081E07314019
chr109878116098781289E07314939
chr109878140598781455E07315184
chr109878166998781843E07315448
chr109878191698781960E07315695
chr109878521698785793E07318995
chr109879817798798257E07331956
chr109879835398798446E07332132
chr109880780698807856E07341585
chr109880789198808026E07341670
chr109872301698723119E074-43102
chr109872315398723443E074-42778
chr109878024098781081E07414019
chr109878116098781289E07414939
chr109878521698785793E07418995
chr109879817798798257E07431956
chr109878024098781081E08114019
chr109878116098781289E08114939
chr109879817798798257E08131956
chr109880666598806741E08140444
chr109880747098807510E08141249
chr109880753998807597E08141318
chr109880771598807755E08141494
chr109880780698807856E08141585
chr109880789198808026E08141670
chr109880803698808111E08141815
chr109880811998808189E08141898
chr109880826098808351E08142039
chr109880842898808478E08142207
chr109880862598808740E08142404
chr109879817798798257E08231956
chr109881280998812864E08246588
chr109881603198816110E08249810