rs11198934

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0088 (2633/29870,GnomAD)
T=0067 (1950/29118,TOPMED)
T=0130 (653/5008,1000G)
T=0114 (440/3854,ALSPAC)
T=0122 (451/3708,TWINSUK)
chr10:119458171 (GRCh38.p7) (10q26.11)
AD
GWASdb2
1   publication(s)
See rs on genome
25 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.119458171C>T
GRCh37.p13 chr 10NC_000010.10:g.121217683C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.998T=0.002
1000GenomesAmericanSub694C=0.890T=0.110
1000GenomesEast AsianSub1008C=0.701T=0.299
1000GenomesEuropeSub1006C=0.913T=0.087
1000GenomesGlobalStudy-wide5008C=0.870T=0.130
1000GenomesSouth AsianSub978C=0.810T=0.190
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.886T=0.114
The Genome Aggregation DatabaseAfricanSub8708C=0.977T=0.023
The Genome Aggregation DatabaseAmericanSub838C=0.900T=0.100
The Genome Aggregation DatabaseEast AsianSub1616C=0.719T=0.281
The Genome Aggregation DatabaseEuropeSub18406C=0.898T=0.101
The Genome Aggregation DatabaseGlobalStudy-wide29870C=0.911T=0.088
The Genome Aggregation DatabaseOtherSub302C=0.910T=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.933T=0.067
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.878T=0.122
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs111989340.00019alcohol dependence20201924

eQTL of rs11198934 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11198934 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10121253817121254967E06736134
chr10121254976121255070E06737293
chr10121254976121255070E06837293
chr10121253817121254967E06936134
chr10121181127121182266E070-35417
chr10121182308121182358E070-35325
chr10121182435121182619E070-35064
chr10121253495121253632E07035812
chr10121253817121254967E07036134
chr10121254976121255070E07037293
chr10121255100121255301E07037417
chr10121181127121182266E071-35417
chr10121253817121254967E07136134
chr10121184179121184232E072-33451
chr10121184286121184497E072-33186
chr10121184502121184576E072-33107
chr10121184598121184658E072-33025
chr10121253495121253632E07235812
chr10121253817121254967E07236134
chr10121171630121174291E073-43392
chr10121248829121249663E07431146
chr10121171630121174291E081-43392
chr10121249761121250077E08132078
chr10121251459121252290E08133776
chr10121263230121263284E08245547