rs11209757

Homo sapiens
T>A / T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0475 (14172/29838,GnomAD)
G=0435 (12687/29118,TOPMED)
T==0463 (2321/5008,1000G)
G=0436 (1681/3854,ALSPAC)
G=0463 (1716/3708,TWINSUK)
chr1:71263217 (GRCh38.p7) (1p31.1)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.71263217T>A
GRCh38.p7 chr 1NC_000001.11:g.71263217T>G
GRCh37.p13 chr 1NC_000001.10:g.71728900T>A
GRCh37.p13 chr 1NC_000001.10:g.71728900T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.588G=0.412
1000GenomesAmericanSub694T=0.390G=0.610
1000GenomesEast AsianSub1008T=0.250G=0.750
1000GenomesEuropeSub1006T=0.569G=0.431
1000GenomesGlobalStudy-wide5008T=0.463G=0.537
1000GenomesSouth AsianSub978T=0.460G=0.540
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.564G=0.436
The Genome Aggregation DatabaseAfricanSub8692T=0.575A=0.000
The Genome Aggregation DatabaseAmericanSub832T=0.390A=0.00,
The Genome Aggregation DatabaseEast AsianSub1568T=0.252A=0.000
The Genome Aggregation DatabaseEuropeSub18446T=0.530A=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29838T=0.525A=0.000
The Genome Aggregation DatabaseOtherSub300T=0.560A=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.564G=0.435
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.537G=0.463
PMID Title Author Journal
23089632A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.Wang JCMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs112097571.29E-05alcohol dependence23089632

eQTL of rs11209757 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11209757 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr18852394088524034E070-46349
chr18856029088560340E070-10043