rs11211074

Homo sapiens
T>C
ZSWIM5 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0350 (10475/29924,GnomAD)
T==0396 (11535/29118,TOPMED)
T==0290 (1451/5008,1000G)
T==0278 (1070/3854,ALSPAC)
T==0282 (1047/3708,TWINSUK)
chr1:45064837 (GRCh38.p7) (1p34.1)
CD
GWASdb2
1   publication(s)
See rs on genome
18 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.45064837T>C
GRCh37.p13 chr 1NC_000001.10:g.45530509T>C

Gene: ZSWIM5, zinc finger SWIM-type containing 5(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ZSWIM5 transcriptNM_020883.1:c.N/AIntron Variant
ZSWIM5 transcript variant X2XM_011541861.2:c.N/AIntron Variant
ZSWIM5 transcript variant X1XM_017001913.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.592C=0.408
1000GenomesAmericanSub694T=0.220C=0.780
1000GenomesEast AsianSub1008T=0.132C=0.868
1000GenomesEuropeSub1006T=0.257C=0.743
1000GenomesGlobalStudy-wide5008T=0.290C=0.710
1000GenomesSouth AsianSub978T=0.130C=0.870
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.278C=0.722
The Genome Aggregation DatabaseAfricanSub8706T=0.566C=0.434
The Genome Aggregation DatabaseAmericanSub836T=0.220C=0.780
The Genome Aggregation DatabaseEast AsianSub1616T=0.123C=0.877
The Genome Aggregation DatabaseEuropeSub18464T=0.276C=0.723
The Genome Aggregation DatabaseGlobalStudy-wide29924T=0.350C=0.649
The Genome Aggregation DatabaseOtherSub302T=0.220C=0.780
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.396C=0.603
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.282C=0.718
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs112110740.00000343cocaine dependence,AA23958962
rs112110740.000239cocaine dependence23958962

eQTL of rs11211074 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11211074 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr14548415645484206E067-46303
chr14548426545484730E067-45779
chr14548415645484206E069-46303
chr14548426545484730E069-45779
chr14548415645484206E070-46303
chr14548426545484730E070-45779
chr14548513245485172E070-45337
chr14556286145562919E07032352
chr14556930045569508E07038791
chr14557019945570287E07039690
chr14548415645484206E071-46303
chr14548426545484730E071-45779
chr14548087345480917E072-49592
chr14548415645484206E072-46303
chr14548426545484730E072-45779
chr14548426545484730E073-45779
chr14548415645484206E074-46303
chr14548426545484730E074-45779