rs11250672

Homo sapiens
G>A
ADARB2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0155 (4665/29928,GnomAD)
A=0154 (4506/29118,TOPMED)
A=0132 (659/5008,1000G)
A=0194 (749/3854,ALSPAC)
A=0195 (722/3708,TWINSUK)
chr10:1623271 (GRCh38.p7) (10p15.3)
AD
GWASdb2
1   publication(s)
See rs on genome
148 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.1623271G>A
GRCh37.p13 chr 10NC_000010.10:g.1665466G>A

Gene: ADARB2, adenosine deaminase, RNA specific B2 (inactive)(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ADARB2 transcriptNM_018702.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.867A=0.133
1000GenomesAmericanSub694G=0.880A=0.120
1000GenomesEast AsianSub1008G=0.917A=0.083
1000GenomesEuropeSub1006G=0.800A=0.200
1000GenomesGlobalStudy-wide5008G=0.868A=0.132
1000GenomesSouth AsianSub978G=0.880A=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.806A=0.194
The Genome Aggregation DatabaseAfricanSub8700G=0.871A=0.129
The Genome Aggregation DatabaseAmericanSub838G=0.880A=0.120
The Genome Aggregation DatabaseEast AsianSub1618G=0.939A=0.061
The Genome Aggregation DatabaseEuropeSub18470G=0.820A=0.179
The Genome Aggregation DatabaseGlobalStudy-wide29928G=0.844A=0.155
The Genome Aggregation DatabaseOtherSub302G=0.860A=0.140
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.845A=0.154
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.805A=0.195
PMID Title Author Journal
22072270Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.Wang KSJ Neural Transm (Vienna)

P-Value

SNP ID p-value Traits Study
rs112506724.99E-05alcohol withdrawal symptoms22072270

eQTL of rs11250672 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11250672 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1016873691687456E06721903
chr1016877841687867E06722318
chr1016881061688156E06722640
chr1016888701688949E06723404
chr1016890611689111E06723595
chr1016506141650685E068-14781
chr1016888701688949E06823404
chr1016890611689111E06823595
chr1017008621701102E06835396
chr1017011651701271E06835699
chr1017013531701670E06835887
chr1017104681710662E06845002
chr1017106831710737E06845217
chr1016877841687867E06922318
chr1016881061688156E06922640
chr1016888701688949E06923404
chr1016890611689111E06923595
chr1016893511689401E06923885
chr1016935951693649E06928129
chr1016944201694786E06928954
chr1016948181694923E06929352
chr1016949811695041E06929515
chr1017008621701102E06935396
chr1017011651701271E06935699
chr1017013531701670E06935887
chr1017061991706317E06940733
chr1017063681706408E06940902
chr1017093771709510E06943911
chr1017096221709848E06944156
chr1017098871709939E06944421
chr1017104681710662E06945002
chr1016390591639150E070-26316
chr1016504761650569E070-14897
chr1016506141650685E070-14781
chr1016516841652015E070-13451
chr1016520371652181E070-13285
chr1016525311652581E070-12885
chr1016792711679517E07013805
chr1016796051679722E07014139
chr1016798451679895E07014379
chr1016799491680042E07014483
chr1016810531681279E07015587
chr1016859681686107E07020502
chr1016862421686322E07020776
chr1016931591693462E07027693
chr1016935951693649E07028129
chr1016937321693846E07028266
chr1016940211694074E07028555
chr1016941701694230E07028704
chr1016942941694369E07028828
chr1017008621701102E07035396
chr1017011651701271E07035699
chr1017013531701670E07035887
chr1017018471701942E07036381
chr1017084901708611E07043024
chr1017087431708842E07043277
chr1017089041708954E07043438
chr1017098871709939E07044421
chr1017104681710662E07045002
chr1017106831710737E07045217
chr1016506141650685E071-14781
chr1016516841652015E071-13451
chr1016873691687456E07121903
chr1016881061688156E07122640
chr1017008621701102E07135396
chr1017011651701271E07135699
chr1017013531701670E07135887
chr1017018471701942E07136381
chr1017066691706749E07141203
chr1017067571706844E07141291
chr1016873691687456E07221903
chr1016877841687867E07222318
chr1016881061688156E07222640
chr1017008621701102E07235396
chr1017011651701271E07235699
chr1017013531701670E07235887
chr1017018471701942E07236381
chr1017066691706749E07241203
chr1016506141650685E073-14781
chr1016862421686322E07320776
chr1017066691706749E07341203
chr1017067571706844E07341291
chr1017069231707154E07341457
chr1016429201643444E074-22022
chr1016506141650685E074-14781
chr1016881061688156E07422640
chr1016888701688949E07423404
chr1016890611689111E07423595
chr1017008621701102E07435396
chr1017061991706317E07440733
chr1017063681706408E07440902
chr1017066691706749E07441203
chr1017067571706844E07441291
chr1017069231707154E07441457
chr1017093771709510E07443911
chr1017096221709848E07444156
chr1017098871709939E07444421
chr1017104681710662E07445002
chr1017106831710737E07445217
chr1016177131617777E081-47689
chr1016201581620219E081-45247
chr1016203321620494E081-44972
chr1016208061620856E081-44610
chr1016335991633680E081-31786
chr1016338421633936E081-31530
chr1016372321637379E081-28087
chr1016506141650685E081-14781
chr1016516841652015E081-13451
chr1016520371652181E081-13285
chr1016744471674515E0818981
chr1016745611674615E0819095
chr1016859681686107E08120502
chr1016862421686322E08120776
chr1016873691687456E08121903
chr1016895991689649E08124133
chr1016935951693649E08128129
chr1016937321693846E08128266
chr1016940211694074E08128555
chr1016941701694230E08128704
chr1016942941694369E08128828
chr1016944201694786E08128954
chr1017008621701102E08135396
chr1017011651701271E08135699
chr1017013531701670E08135887
chr1017104681710662E08145002
chr1017125801712666E08147114
chr1017128321713200E08147366
chr1016172021617311E082-48155
chr1016174901617648E082-47818
chr1016177131617777E082-47689
chr1016435891643938E082-21528
chr1016504761650569E082-14897
chr1016506141650685E082-14781
chr1016516841652015E082-13451
chr1016520371652181E082-13285
chr1016859681686107E08220502
chr1016862421686322E08220776
chr1016940211694074E08228555
chr1016941701694230E08228704
chr1016942941694369E08228828
chr1016944201694786E08228954
chr1016948181694923E08229352
chr1016949811695041E08229515
chr1017008621701102E08235396
chr1017011651701271E08235699
chr1017013531701670E08235887
chr1017061991706317E08240733
chr1017063681706408E08240902