rs11251836

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0124 (3704/29720,GnomAD)
T=0133 (3874/29118,TOPMED)
T=0101 (504/5008,1000G)
T=0087 (335/3854,ALSPAC)
T=0093 (345/3708,TWINSUK)
chr10:3293255 (GRCh38.p7) (10p15.2)
AD
GWASdb2
1   publication(s)
See rs on genome
71 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.3293255G>T
GRCh37.p13 chr 10NC_000010.10:g.3335447G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.814T=0.186
1000GenomesAmericanSub694G=0.920T=0.080
1000GenomesEast AsianSub1008G=0.958T=0.042
1000GenomesEuropeSub1006G=0.908T=0.092
1000GenomesGlobalStudy-wide5008G=0.899T=0.101
1000GenomesSouth AsianSub978G=0.930T=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.913T=0.087
The Genome Aggregation DatabaseAfricanSub8636G=0.811T=0.189
The Genome Aggregation DatabaseAmericanSub834G=0.930T=0.070
The Genome Aggregation DatabaseEast AsianSub1610G=0.955T=0.045
The Genome Aggregation DatabaseEuropeSub18338G=0.896T=0.103
The Genome Aggregation DatabaseGlobalStudy-wide29720G=0.875T=0.124
The Genome Aggregation DatabaseOtherSub302G=0.880T=0.120
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.867T=0.133
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.907T=0.093
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs112518360.0000288alcoholismpha002892
rs112518360.000029alcohol dependence20201924

eQTL of rs11251836 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11251836 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1033658763367357E06730429
chr1033727293373703E06837282
chr1032906563291770E069-43677
chr1033355763335637E069129
chr1033356453335718E069198
chr1033357463336169E069299
chr1033362193336853E069772
chr1033658763367357E06930429
chr1033119393312403E070-23044
chr1033124943312554E070-22893
chr1033658763367357E07030429
chr1033674623367591E07032015
chr1033727293373703E07037282
chr1033825823382664E07047135
chr1033355763335637E071129
chr1033356453335718E071198
chr1033357463336169E071299
chr1033362193336853E071772
chr1033372453337407E0711798
chr1033375543337648E0712107
chr1033657593365856E07130312
chr1033658763367357E07130429
chr1033657593365856E07230312
chr1033658763367357E07230429
chr1033657593365856E07330312
chr1033658763367357E07330429
chr1033658763367357E07430429
chr1033126453314040E081-21407
chr1033142813314378E081-21069
chr1033144553314517E081-20930
chr1033145773314782E081-20665
chr1033232303323405E081-12042
chr1033346833335542E0810
chr1033355763335637E081129
chr1033356453335718E081198
chr1033357463336169E081299
chr1033362193336853E081772
chr1033369453337062E0811498
chr1033372453337407E0811798
chr1033375543337648E0812107
chr1033377423337960E0812295
chr1033471213347184E08111674
chr1033472603347594E08111813
chr1033478713347933E08112424
chr1033481243348674E08112677
chr1033487223348843E08113275
chr1033489123348963E08113465
chr1033526043353118E08117157
chr1033531593353210E08117712
chr1033547143355077E08119267
chr1033657593365856E08130312
chr1033658763367357E08130429
chr1033674623367591E08132015
chr1033682753368456E08132828
chr1033686193369443E08133172
chr1033727293373703E08137282
chr1033739213373997E08138474
chr1033346833335542E0820
chr1033355763335637E082129
chr1033356453335718E082198
chr1033357463336169E082299
chr1033362193336853E082772
chr1033369453337062E0821498
chr1033377423337960E0822295
chr1033492763349395E08213829
chr1033526043353118E08217157
chr1033531593353210E08217712
chr1033657593365856E08230312
chr1033658763367357E08230429
chr1033674623367591E08232015
chr1033727293373703E08237282










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1033191623319212E067-16235
chr1033193213319371E067-16076
chr1033193963319446E067-16001
chr1033191623319212E072-16235
chr1033193213319371E072-16076
chr1033193963319446E072-16001
chr1033195373319659E072-15788
chr1033606963360991E07225249
chr1033611593361344E07225712