rs112525781

Homo sapiens
C>T
LOC105373640 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0016 (493/29992,GnomAD)
T=0023 (680/29118,TOPMED)
T=0015 (76/5008,1000G)
T=0000 (1/3854,ALSPAC)
T=0001 (3/3708,TWINSUK)
chr2:138961777 (GRCh38.p7) (2q22.1)
AD
GWASCatalog
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.138961777C>T
GRCh37.p13 chr 2NC_000002.11:g.139719347C>T

Gene: LOC105373640, uncharacterized LOC105373640(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105373640 transcriptXR_923371.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.946T=0.054
1000GenomesAmericanSub694C=0.990T=0.010
1000GenomesEast AsianSub1008C=1.000T=0.000
1000GenomesEuropeSub1006C=0.999T=0.001
1000GenomesGlobalStudy-wide5008C=0.985T=0.015
1000GenomesSouth AsianSub978C=1.000T=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=1.000T=0.000
The Genome Aggregation DatabaseAfricanSub8726C=0.944T=0.056
The Genome Aggregation DatabaseAmericanSub838C=1.000T=0.000
The Genome Aggregation DatabaseEast AsianSub1622C=1.000T=0.000
The Genome Aggregation DatabaseEuropeSub18504C=0.999T=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29992C=0.983T=0.016
The Genome Aggregation DatabaseOtherSub302C=1.000T=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.976T=0.023
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.999T=0.001
PMID Title Author Journal
29071344Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.Zhou HJAMA Psychiatry

P-Value

SNP ID p-value Traits Study
rs1125257819E-06alcohol dependence29071344

eQTL of rs112525781 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs112525781 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.