rs1125832

Homo sapiens
T>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0249 (7479/29924,GnomAD)
A=0232 (6772/29118,TOPMED)
A=0201 (1006/5008,1000G)
A=0335 (1292/3854,ALSPAC)
A=0337 (1251/3708,TWINSUK)
chr16:52387228 (GRCh38.p7) (16q12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
16 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.52387228T>A
GRCh37.p13 chr 16NC_000016.9:g.52421140T>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.886A=0.114
1000GenomesAmericanSub694T=0.770A=0.230
1000GenomesEast AsianSub1008T=0.814A=0.186
1000GenomesEuropeSub1006T=0.698A=0.302
1000GenomesGlobalStudy-wide5008T=0.799A=0.201
1000GenomesSouth AsianSub978T=0.790A=0.210
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.665A=0.335
The Genome Aggregation DatabaseAfricanSub8708T=0.844A=0.156
The Genome Aggregation DatabaseAmericanSub838T=0.720A=0.280
The Genome Aggregation DatabaseEast AsianSub1614T=0.831A=0.169
The Genome Aggregation DatabaseEuropeSub18464T=0.701A=0.298
The Genome Aggregation DatabaseGlobalStudy-wide29924T=0.750A=0.249
The Genome Aggregation DatabaseOtherSub300T=0.630A=0.370
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.767A=0.232
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.663A=0.337
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs11258320.000338alcohol dependence21314694

eQTL of rs1125832 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1125832 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr165246928252470096E06948142
chr165241708952417397E070-3743
chr165241756152417627E070-3513
chr165241770552417826E070-3314
chr165241792152418002E070-3138
chr165244083252440937E07019692
chr165244101752441126E07019877
chr165244151352441778E07020373
chr165246900552469055E07047865
chr165246928252470096E07048142
chr165247022352470320E07049083
chr165247081752470867E07049677
chr165246928252470096E07148142
chr165246928252470096E07248142
chr165246928252470096E07448142
chr165246928252470096E08148142