rs1146833

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0391 (11722/29914,GnomAD)
C==0379 (11056/29116,TOPMED)
C==0423 (2117/5008,1000G)
C==0326 (1256/3854,ALSPAC)
C==0351 (1302/3708,TWINSUK)
chr13:68250938 (GRCh38.p7) (13q21.33)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.68250938C>T
GRCh37.p13 chr 13NC_000013.10:g.68825070C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.462T=0.538
1000GenomesAmericanSub694C=0.270T=0.730
1000GenomesEast AsianSub1008C=0.515T=0.485
1000GenomesEuropeSub1006C=0.356T=0.644
1000GenomesGlobalStudy-wide5008C=0.423T=0.577
1000GenomesSouth AsianSub978C=0.450T=0.550
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.326T=0.674
The Genome Aggregation DatabaseAfricanSub8694C=0.448T=0.552
The Genome Aggregation DatabaseAmericanSub836C=0.260T=0.740
The Genome Aggregation DatabaseEast AsianSub1614C=0.508T=0.492
The Genome Aggregation DatabaseEuropeSub18468C=0.362T=0.637
The Genome Aggregation DatabaseGlobalStudy-wide29914C=0.391T=0.608
The Genome Aggregation DatabaseOtherSub302C=0.340T=0.660
Trans-Omics for Precision MedicineGlobalStudy-wide29116C=0.379T=0.620
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.351T=0.649
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs11468330.000525alcohol dependence20201924

eQTL of rs1146833 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1146833 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr136878933068789483E070-35587
chr136882836668828595E0713296
chr136882836668828595E0743296