rs115460205

Homo sapiens
C>T
FSTL5 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0046 (1379/29936,GnomAD)
T=0040 (1179/29118,TOPMED)
T=0025 (124/5008,1000G)
T=0077 (295/3854,ALSPAC)
T=0080 (298/3708,TWINSUK)
chr4:161890417 (GRCh38.p7) (4q32.2)
AD
GWASCatalog
1   publication(s)
See rs on genome
17 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.161890417C>T
GRCh37.p13 chr 4NC_000004.11:g.162811569C>T

Gene: FSTL5, follistatin like 5(minus strand)

Molecule type Change Amino acid[Codon] SO Term
FSTL5 transcript variant 2NM_001128427.2:c.N/AIntron Variant
FSTL5 transcript variant 3NM_001128428.2:c.N/AIntron Variant
FSTL5 transcript variant 1NM_020116.4:c.N/AIntron Variant
FSTL5 transcript variant X1XM_011532126.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.994T=0.006
1000GenomesAmericanSub694C=0.980T=0.020
1000GenomesEast AsianSub1008C=1.000T=0.000
1000GenomesEuropeSub1006C=0.926T=0.074
1000GenomesGlobalStudy-wide5008C=0.975T=0.025
1000GenomesSouth AsianSub978C=0.970T=0.030
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.923T=0.077
The Genome Aggregation DatabaseAfricanSub8726C=0.985T=0.015
The Genome Aggregation DatabaseAmericanSub834C=0.960T=0.040
The Genome Aggregation DatabaseEast AsianSub1612C=0.999T=0.001
The Genome Aggregation DatabaseEuropeSub18462C=0.934T=0.065
The Genome Aggregation DatabaseGlobalStudy-wide29936C=0.953T=0.046
The Genome Aggregation DatabaseOtherSub302C=0.970T=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.959T=0.040
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.920T=0.080
PMID Title Author Journal
28990359Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.Polimanti RAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs1154602054E-08alcohol dependence28990359

eQTL of rs115460205 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs115460205 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4162851166162851415E06839597
chr4162851166162851415E06939597
chr4162852310162852508E06940741
chr4162802887162802937E070-8632
chr4162804397162804447E070-7122
chr4162804557162804623E070-6946
chr4162814147162814303E0722578
chr4162851166162851415E07239597
chr4162802887162802937E074-8632
chr4162851166162851415E07439597
chr4162852310162852508E07440741
chr4162762964162763255E081-48314
chr4162828026162828464E08216457
chr4162828925162828988E08217356
chr4162841210162841339E08229641
chr4162841512162841633E08229943
chr4162841997162842061E08230428







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr4162847692162847922E06836123