rs11564346

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0493 (14733/29880,GnomAD)
C==0472 (13769/29118,TOPMED)
C==0429 (2150/5008,1000G)
C==0496 (1912/3854,ALSPAC)
C==0491 (1821/3708,TWINSUK)
chr18:28246998 (GRCh38.p7) (18q12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
12 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.28246998C>T
GRCh37.p13 chr 18NC_000018.9:g.25826962C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.474T=0.526
1000GenomesAmericanSub694C=0.500T=0.500
1000GenomesEast AsianSub1008C=0.314T=0.686
1000GenomesEuropeSub1006C=0.480T=0.520
1000GenomesGlobalStudy-wide5008C=0.429T=0.571
1000GenomesSouth AsianSub978C=0.380T=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.496T=0.504
The Genome Aggregation DatabaseAfricanSub8704C=0.484T=0.516
The Genome Aggregation DatabaseAmericanSub832C=0.500T=0.500
The Genome Aggregation DatabaseEast AsianSub1620C=0.324T=0.676
The Genome Aggregation DatabaseEuropeSub18422C=0.512T=0.487
The Genome Aggregation DatabaseGlobalStudy-wide29880C=0.493T=0.506
The Genome Aggregation DatabaseOtherSub302C=0.480T=0.520
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.472T=0.527
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.491T=0.509
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs115643460.000744alcohol dependence20201924

eQTL of rs11564346 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11564346 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr182586121125861352E07034249
chr182586143425861657E07034472
chr182586197125862150E07035009

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr182577868025778836E067-48126
chr182577885225778902E067-48060
chr182577868025778836E068-48126
chr182577885225778902E068-48060
chr182577868025778836E069-48126
chr182577885225778902E069-48060
chr182577868025778836E071-48126
chr182577885225778902E071-48060
chr182577868025778836E072-48126
chr182577885225778902E072-48060
chr182577868025778836E074-48126
chr182577885225778902E074-48060