rs115664995

Homo sapiens
G>T
RSU1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0010 (299/29992,GnomAD)
T=0017 (500/29118,TOPMED)
T=0010 (51/5008,1000G)
chr10:16796593 (GRCh38.p7) (10p13)
CD
GWASdb2
1   publication(s)
See rs on genome
45 Enhancers around
12 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.16796593G>T
GRCh37.p13 chr 10NC_000010.10:g.16838592G>T

Gene: RSU1, Ras suppressor protein 1(minus strand)

Molecule type Change Amino acid[Codon] SO Term
RSU1 transcript variant 1NM_012425.3:c.N/AIntron Variant
RSU1 transcript variant 2NM_152724.2:c.N/AIntron Variant
RSU1 transcript variant X1XM_005252552.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.964T=0.036
1000GenomesAmericanSub694G=0.990T=0.010
1000GenomesEast AsianSub1008G=1.000T=0.000
1000GenomesEuropeSub1006G=1.000T=0.000
1000GenomesGlobalStudy-wide5008G=0.990T=0.010
1000GenomesSouth AsianSub978G=1.000T=0.000
The Genome Aggregation DatabaseAfricanSub8724G=0.966T=0.034
The Genome Aggregation DatabaseAmericanSub838G=1.000T=0.000
The Genome Aggregation DatabaseEast AsianSub1620G=1.000T=0.000
The Genome Aggregation DatabaseEuropeSub18508G=0.999T=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29992G=0.990T=0.010
The Genome Aggregation DatabaseOtherSub302G=1.000T=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.982T=0.017
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs1156649950.000208cocaine dependence23958962

eQTL of rs115664995 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs115664995 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr101681940916819968E067-18624
chr101685766516857786E06719073
chr101685786816858044E06719276
chr101681940916819968E068-18624
chr101685766516857786E06819073
chr101685786816858044E06819276
chr101687446016875066E06935868
chr101682082216820993E070-17599
chr101682251816822573E070-16019
chr101685705616857212E07018464
chr101685766516857786E07019073
chr101685786816858044E07019276
chr101688517816885849E07146586
chr101681940916819968E073-18624
chr101685693916857032E07318347
chr101685705616857212E07318464
chr101685723316857330E07318641
chr101685766516857786E07319073
chr101685786816858044E07319276
chr101686053316860698E07321941
chr101687446016875066E07335868
chr101687520316875254E07336611
chr101681940916819968E081-18624
chr101682014616820318E081-18274
chr101682033016820380E081-18212
chr101682082216820993E081-17599
chr101682111716821167E081-17425
chr101682134016821946E081-16646
chr101682228416822324E081-16268
chr101682251816822573E081-16019
chr101682264316822810E081-15782
chr101682351316823614E081-14978
chr101682373416823784E081-14808
chr101682481316824865E081-13727
chr101682487816824928E081-13664
chr101685766516857786E08119073
chr101685786816858044E08119276
chr101687415616874256E08135564
chr101687446016875066E08135868
chr101682082216820993E082-17599
chr101682111716821167E082-17425
chr101682134016821946E082-16646
chr101682228416822324E082-16268
chr101682251816822573E082-16019
chr101685786816858044E08219276








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr101685865216860517E06720060
chr101685865216860517E06820060
chr101685865216860517E06920060
chr101685865216860517E07020060
chr101685865216860517E07120060
chr101686968916869820E07131097
chr101685865216860517E07220060
chr101686968916869820E07231097
chr101685865216860517E07320060
chr101685865216860517E07420060
chr101685865216860517E08120060
chr101685865216860517E08220060