SNP Detail Info-rs1157072

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

NEGR1 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0037 (1136/29958,GnomAD)
G=0026 (775/29118,TOPMED)
G=0016 (82/5008,1000G)
G=0053 (205/3854,ALSPAC)
G=0049 (181/3708,TWINSUK)

Position: chr1:72169229 (GRCh38.p7) (1p31.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 3 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.72169229A>G
GRCh37.p13 chr 1	NC_000001.10:g.72634912A>G

Molecule type	Change	Amino acid[Codon]	SO Term
NEGR1 transcript	NM_173808.2:c.	N/A	Intron Variant
NEGR1 transcript variant X1	XM_011541200.2:c.	N/A	Intron Variant
NEGR1 transcript variant X2	XM_011541201.2:c.	N/A	Intron Variant
NEGR1 transcript variant X3	XM_017000961.1:c.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.999	G=0.001
1000Genomes	American	Sub	694	A=0.980	G=0.020
1000Genomes	East Asian	Sub	1008	A=1.000	G=0.000
1000Genomes	Europe	Sub	1006	A=0.956	G=0.044
1000Genomes	Global	Study-wide	5008	A=0.984	G=0.016
1000Genomes	South Asian	Sub	978	A=0.980	G=0.020
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.947	G=0.053
The Genome Aggregation Database	African	Sub	8734	A=0.990	G=0.010
The Genome Aggregation Database	American	Sub	836	A=0.980	G=0.020
The Genome Aggregation Database	East Asian	Sub	1614	A=1.000	G=0.000
The Genome Aggregation Database	Europe	Sub	18472	A=0.944	G=0.056
The Genome Aggregation Database	Global	Study-wide	29958	A=0.962	G=0.037
The Genome Aggregation Database	Other	Sub	302	A=0.980	G=0.020
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.973	G=0.026
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.951	G=0.049

PMID	Title	Author	Journal
19268276	Genome-wide association study of smoking initiation and current smoking.	Vink JM	Am J Hum Genet

SNP ID	p-value	Traits	Study
rs1157072	0.000643	nicotine smoking	19268276

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	72663620	72663710	E072	28708
chr1	72663904	72663958	E072	28992
chr1	72663904	72663958	E074	28992

rs1157072