rs11576745

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0404 (12093/29874,GnomAD)
T=0372 (10834/29118,TOPMED)
T=0390 (1954/5008,1000G)
T=0432 (1664/3854,ALSPAC)
T=0420 (1558/3708,TWINSUK)
chr1:84774563 (GRCh38.p7) (1p22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
101 Enhancers around
13 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.84774563C>T
GRCh37.p13 chr 1NC_000001.10:g.85240246C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.672T=0.328
1000GenomesAmericanSub694C=0.670T=0.330
1000GenomesEast AsianSub1008C=0.564T=0.436
1000GenomesEuropeSub1006C=0.624T=0.376
1000GenomesGlobalStudy-wide5008C=0.610T=0.390
1000GenomesSouth AsianSub978C=0.510T=0.490
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.568T=0.432
The Genome Aggregation DatabaseAfricanSub8686C=0.628T=0.372
The Genome Aggregation DatabaseAmericanSub836C=0.650T=0.350
The Genome Aggregation DatabaseEast AsianSub1614C=0.546T=0.454
The Genome Aggregation DatabaseEuropeSub18438C=0.579T=0.420
The Genome Aggregation DatabaseGlobalStudy-wide29874C=0.595T=0.404
The Genome Aggregation DatabaseOtherSub300C=0.720T=0.280
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.627T=0.372
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.580T=0.420
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs115767450.000913alcohol dependence21314694

eQTL of rs11576745 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11576745 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr18520586885205999E067-34247
chr18522556685225733E067-14513
chr18522556685225733E068-14513
chr18522953885229737E068-10509
chr18522979185229922E068-10324
chr18522998485230293E068-9953
chr18523972485239855E068-391
chr18524040585240617E068159
chr18524092385241184E068677
chr18524503985245280E0684793
chr18524565685246066E0685410
chr18527614285276230E06835896
chr18520586885205999E069-34247
chr18520610385206199E069-34047
chr18521894185219086E069-21160
chr18521910485219680E069-20566
chr18522556685225733E069-14513
chr18522998485230293E069-9953
chr18523777185238626E069-1620
chr18523972485239855E069-391
chr18524503985245280E0694793
chr18524565685246066E0695410
chr18524612485246255E0695878
chr18525096485251378E06910718
chr18522556685225733E070-14513
chr18522587085225950E070-14296
chr18522600585226081E070-14165
chr18522842085228627E070-11619
chr18522953885229737E070-10509
chr18522979185229922E070-10324
chr18522998485230293E070-9953
chr18523777185238626E070-1620
chr18523877285239197E070-1049
chr18521910485219680E071-20566
chr18521974685219988E071-20258
chr18522556685225733E071-14513
chr18522587085225950E071-14296
chr18522953885229737E071-10509
chr18522979185229922E071-10324
chr18523777185238626E071-1620
chr18523877285239197E071-1049
chr18524040585240617E071159
chr18524503985245280E0714793
chr18524565685246066E0715410
chr18524612485246255E0715878
chr18525096485251378E07110718
chr18522587085225950E072-14296
chr18523972485239855E072-391
chr18524040585240617E072159
chr18524092385241184E072677
chr18524471785244930E0724471
chr18524503985245280E0724793
chr18521894185219086E073-21160
chr18521910485219680E073-20566
chr18521974685219988E073-20258
chr18522556685225733E073-14513
chr18522587085225950E073-14296
chr18523777185238626E073-1620
chr18523972485239855E073-391
chr18520586885205999E081-34247
chr18521446285214623E081-25623
chr18521501985215432E081-24814
chr18521566685216431E081-23815
chr18521655385216603E081-23643
chr18521894185219086E081-21160
chr18521910485219680E081-20566
chr18521974685219988E081-20258
chr18522098285221084E081-19162
chr18522225985222350E081-17896
chr18522251385222662E081-17584
chr18522312385223309E081-16937
chr18522351485223568E081-16678
chr18522556685225733E081-14513
chr18522587085225950E081-14296
chr18522600585226081E081-14165
chr18522998485230293E081-9953
chr18523777185238626E081-1620
chr18523972485239855E081-391
chr18524040585240617E081159
chr18527614285276230E08135896
chr18527623485276288E08135988
chr18520586885205999E082-34247
chr18520610385206199E082-34047
chr18520620785206509E082-33737
chr18521501985215432E082-24814
chr18521566685216431E082-23815
chr18521894185219086E082-21160
chr18521910485219680E082-20566
chr18521974685219988E082-20258
chr18522098285221084E082-19162
chr18522312385223309E082-16937
chr18522351485223568E082-16678
chr18522587085225950E082-14296
chr18522600585226081E082-14165
chr18522953885229737E082-10509
chr18522979185229922E082-10324
chr18522998485230293E082-9953
chr18523777185238626E082-1620
chr18523877285239197E082-1049
chr18523972485239855E082-391
chr18524040585240617E082159









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr18524778285247897E0677536
chr18524795085248545E0677704
chr18524778285247897E0687536
chr18524795085248545E0687704
chr18524778285247897E0697536
chr18524795085248545E0697704
chr18524778285247897E0707536
chr18524795085248545E0707704
chr18524778285247897E0717536
chr18524795085248545E0717704
chr18524778285247897E0727536
chr18524795085248545E0727704
chr18524795085248545E0827704