SNP Detail Info-rs11588508

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0262 (7833/29876,GnomAD)
G=0194 (5676/29118,TOPMED)
G=0201 (1008/5008,1000G)
G=0338 (1304/3854,ALSPAC)
G=0326 (1209/3708,TWINSUK)

Position: chr1:82737253 (GRCh38.p7) (1p31.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 1 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.82737253A>G
GRCh37.p13 chr 1	NC_000001.10:g.83202936A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.967	G=0.033
1000Genomes	American	Sub	694	A=0.750	G=0.250
1000Genomes	East Asian	Sub	1008	A=0.765	G=0.235
1000Genomes	Europe	Sub	1006	A=0.715	G=0.285
1000Genomes	Global	Study-wide	5008	A=0.799	G=0.201
1000Genomes	South Asian	Sub	978	A=0.730	G=0.270
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.662	G=0.338
The Genome Aggregation Database	African	Sub	8730	A=0.924	G=0.076
The Genome Aggregation Database	American	Sub	836	A=0.750	G=0.250
The Genome Aggregation Database	East Asian	Sub	1556	A=0.742	G=0.258
The Genome Aggregation Database	Europe	Sub	18452	A=0.648	G=0.351
The Genome Aggregation Database	Global	Study-wide	29876	A=0.737	G=0.262
The Genome Aggregation Database	Other	Sub	302	A=0.780	G=0.220
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.805	G=0.194
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.674	G=0.326

PMID	Title	Author	Journal
21703634	A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.	Wang KS	J Psychiatr Res

SNP ID	p-value	Traits	Study
rs11588508	5.61E-05	alcohol dependence	21703634

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs11588508