rs11588936

Homo sapiens
T>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0262 (7819/29842,GnomAD)
A=0194 (5675/29118,TOPMED)
A=0201 (1008/5008,1000G)
A=0338 (1302/3854,ALSPAC)
A=0326 (1209/3708,TWINSUK)
chr1:82737456 (GRCh38.p7) (1p31.1)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.82737456T>A
GRCh37.p13 chr 1NC_000001.10:g.83203139T>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.967A=0.033
1000GenomesAmericanSub694T=0.750A=0.250
1000GenomesEast AsianSub1008T=0.765A=0.235
1000GenomesEuropeSub1006T=0.715A=0.285
1000GenomesGlobalStudy-wide5008T=0.799A=0.201
1000GenomesSouth AsianSub978T=0.730A=0.270
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.662A=0.338
The Genome Aggregation DatabaseAfricanSub8722T=0.924A=0.076
The Genome Aggregation DatabaseAmericanSub838T=0.750A=0.250
The Genome Aggregation DatabaseEast AsianSub1548T=0.744A=0.256
The Genome Aggregation DatabaseEuropeSub18434T=0.648A=0.351
The Genome Aggregation DatabaseGlobalStudy-wide29842T=0.738A=0.262
The Genome Aggregation DatabaseOtherSub300T=0.780A=0.220
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.805A=0.194
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.674A=0.326
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs115889365.43E-05alcohol dependence21703634

eQTL of rs11588936 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11588936 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr18325230883252362E06849169
chr18325294683253021E06949807
chr18325294683253021E08249807