rs11593780

Homo sapiens
C>G / C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0085 (2570/29966,GnomAD)
T=0094 (2748/29118,TOPMED)
T=0055 (277/5008,1000G)
chr10:111098817 (GRCh38.p7) (10q25.2)
AD
GWASdb2
1   publication(s)
See rs on genome
18 Enhancers around
5 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.111098817C>G
GRCh38.p7 chr 10NC_000010.11:g.111098817C>T
GRCh37.p13 chr 10NC_000010.10:g.112858575C>G
GRCh37.p13 chr 10NC_000010.10:g.112858575C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.857T=0.143
1000GenomesAmericanSub694C=0.970T=0.030
1000GenomesEast AsianSub1008C=1.000T=0.000
1000GenomesEuropeSub1006C=0.946T=0.054
1000GenomesGlobalStudy-wide5008C=0.945T=0.055
1000GenomesSouth AsianSub978C=0.990T=0.010
The Genome Aggregation DatabaseAfricanSub8720C=0.849T=0.151
The Genome Aggregation DatabaseAmericanSub838C=0.970T=0.030
The Genome Aggregation DatabaseEast AsianSub1622C=0.999T=0.001
The Genome Aggregation DatabaseEuropeSub18484C=0.934T=0.065
The Genome Aggregation DatabaseGlobalStudy-wide29966C=0.914T=0.085
The Genome Aggregation DatabaseOtherSub302C=0.970T=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.905T=0.094
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs115937800.000539alcohol dependence21314694

eQTL of rs11593780 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11593780 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr109708876897088849E06730770
chr109708919897089282E06731200
chr109709482597095015E06836827
chr109708757497087624E07129576
chr109708775997087809E07129761
chr109706301297063095E0725014
chr109706313297063372E0725134
chr109706339797063698E0725399
chr109708693397087488E07228935
chr109708757497087624E07229576
chr109708775997087809E07229761
chr109709574697095922E07237748
chr109709593897096193E07237940
chr109709623297096364E07238234
chr109709638397096433E07238385
chr109708693397087488E07328935
chr109708757497087624E07329576
chr109708775997087809E07329761





Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr109704874997051414E067-6584
chr109704874997051414E068-6584
chr109704874997051414E071-6584
chr109704874997051414E073-6584
chr109704874997051414E082-6584