rs11606101

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0187 (5607/29916,GnomAD)
C=0187 (5450/29118,TOPMED)
C=0192 (960/5008,1000G)
C=0173 (666/3854,ALSPAC)
C=0183 (678/3708,TWINSUK)
chr11:95557357 (GRCh38.p7) (11q21)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.95557357T>C
GRCh37.p13 chr 11NC_000011.9:g.95290521T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.826C=0.174
1000GenomesAmericanSub694T=0.610C=0.390
1000GenomesEast AsianSub1008T=0.833C=0.167
1000GenomesEuropeSub1006T=0.829C=0.171
1000GenomesGlobalStudy-wide5008T=0.808C=0.192
1000GenomesSouth AsianSub978T=0.880C=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.827C=0.173
The Genome Aggregation DatabaseAfricanSub8708T=0.832C=0.168
The Genome Aggregation DatabaseAmericanSub834T=0.620C=0.380
The Genome Aggregation DatabaseEast AsianSub1606T=0.785C=0.215
The Genome Aggregation DatabaseEuropeSub18466T=0.813C=0.186
The Genome Aggregation DatabaseGlobalStudy-wide29916T=0.812C=0.187
The Genome Aggregation DatabaseOtherSub302T=0.870C=0.130
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.812C=0.187
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.817C=0.183
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs116061010.000529nicotine dependence17158188

eQTL of rs11606101 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11606101 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr119530374695304096E06713225
chr119530419195304231E06713670
chr119530432895304396E06713807
chr119530515995305210E06714638
chr119530917495310091E06718653
chr119531013895310212E06719617
chr119525769895258226E068-32295
chr119528925495290498E068-23
chr119529051995290667E0680
chr119529702695297411E0686505
chr119529742295297548E0686901
chr119529766995297853E0687148
chr119529882795299312E0688306
chr119529938995299798E0688868
chr119530303595303085E06812514
chr119530374695304096E06813225
chr119530515995305210E06814638
chr119530523395305273E06814712
chr119529702695297411E0696505
chr119529742295297548E0696901
chr119529766995297853E0697148
chr119529882795299312E0698306
chr119529938995299798E0698868
chr119530374695304096E06913225
chr119530419195304231E06913670
chr119530432895304396E06913807
chr119532547195326093E06934950
chr119532617495326284E06935653
chr119534009395340170E06949572
chr119529882795299312E0708306
chr119529938995299798E0708868
chr119528925495290498E071-23
chr119529702695297411E0716505
chr119529742295297548E0716901
chr119529766995297853E0717148
chr119529882795299312E0718306
chr119529938995299798E0718868
chr119530419195304231E07113670
chr119530432895304396E07113807
chr119530515995305210E07114638
chr119530523395305273E07114712
chr119530917495310091E07118653
chr119531951395319857E07128992
chr119528709195287816E072-2705
chr119528925495290498E072-23
chr119529742295297548E0726901
chr119529882795299312E0728306
chr119529938995299798E0728868
chr119530374695304096E07213225
chr119530419195304231E07213670
chr119530432895304396E07213807
chr119530515995305210E07214638
chr119530523395305273E07214712
chr119532368595323791E07233164
chr119532547195326093E07234950
chr119532617495326284E07235653
chr119528925495290498E073-23
chr119531013895310212E07319617
chr119532547195326093E07334950
chr119530515995305210E07414638
chr119530917495310091E07418653
chr119531013895310212E07419617
chr119531916895319473E07428647
chr119531951395319857E07428992
chr119528925495290498E081-23
chr119529051995290667E0810
chr119529068695290795E081165
chr119529882795299312E0818306
chr119529938995299798E0818868
chr119530419195304231E08113670
chr119530432895304396E08113807
chr119528925495290498E082-23