rs11616603

Homo sapiens
A>G
MYO16 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0151 (4528/29938,GnomAD)
G=0122 (3558/29118,TOPMED)
G=0133 (665/5008,1000G)
G=0186 (715/3854,ALSPAC)
G=0188 (696/3708,TWINSUK)
chr13:108519067 (GRCh38.p7) (13q33.3)
AD
GWASCatalog
1   publication(s)
See rs on genome
16 Enhancers around
7 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.108519067A>G
GRCh37.p13 chr 13NC_000013.10:g.109171415A>G

Gene: MYO16, myosin XVI(plus strand)

Molecule type Change Amino acid[Codon] SO Term
MYO16 transcript variant 1NM_001198950.1:c.N/AGenic Upstream Transcript Variant
MYO16 transcript variant 2NM_015011.1:c.N/AGenic Upstream Transcript Variant
MYO16 transcript variant X1XM_011521062.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.980G=0.020
1000GenomesAmericanSub694A=0.820G=0.180
1000GenomesEast AsianSub1008A=0.812G=0.188
1000GenomesEuropeSub1006A=0.804G=0.196
1000GenomesGlobalStudy-wide5008A=0.867G=0.133
1000GenomesSouth AsianSub978A=0.870G=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.814G=0.186
The Genome Aggregation DatabaseAfricanSub8724A=0.963G=0.037
The Genome Aggregation DatabaseAmericanSub836A=0.830G=0.170
The Genome Aggregation DatabaseEast AsianSub1612A=0.850G=0.150
The Genome Aggregation DatabaseEuropeSub18464A=0.795G=0.204
The Genome Aggregation DatabaseGlobalStudy-wide29938A=0.848G=0.151
The Genome Aggregation DatabaseOtherSub302A=0.820G=0.180
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.877G=0.122
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.812G=0.188
PMID Title Author Journal
29460428Genomewide Association Study of Alcohol Dependence and Related Traits in a Thai Population.Gelernter JAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs116166039E-06alcohol dependence29460428

eQTL of rs11616603 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11616603 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr13109153220109153294E081-18121
chr13109178241109178444E0816826
chr13109178453109178938E0817038
chr13109178996109179097E0817581
chr13109180855109180958E0819440
chr13109212142109212207E08140727
chr13109212398109212454E08140983
chr13109212539109212739E08141124
chr13109178241109178444E0826826
chr13109178453109178938E0827038
chr13109178996109179097E0827581
chr13109179238109179420E0827823
chr13109179595109179772E0828180
chr13109212142109212207E08240727
chr13109212398109212454E08240983
chr13109212539109212739E08241124


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr13109147085109149652E068-21763
chr13109147085109149652E069-21763
chr13109147085109149652E071-21763
chr13109147085109149652E072-21763
chr13109147085109149652E073-21763
chr13109147085109149652E081-21763
chr13109147085109149652E082-21763