rs11623923

Homo sapiens
G>A
SLC35F4 : Intron Variant
LOC105370519 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0122 (3587/29328,GnomAD)
A=0111 (3236/29118,TOPMED)
A=0091 (456/5008,1000G)
A=0166 (641/3854,ALSPAC)
A=0165 (610/3708,TWINSUK)
chr14:57576035 (GRCh38.p7) (14q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
9 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.57576035G>A
GRCh37.p13 chr 14NC_000014.8:g.58042753G>A

Gene: SLC35F4, solute carrier family 35 member F4(minus strand)

Molecule type Change Amino acid[Codon] SO Term
SLC35F4 transcript variant 2NM_001206920.1:c.N/AIntron Variant
SLC35F4 transcript variant 1NM_001306087.1:c.N/AIntron Variant
SLC35F4 transcript variant X1XM_011536720.2:c.N/AIntron Variant
SLC35F4 transcript variant X3XM_011536721.2:c.N/AIntron Variant
SLC35F4 transcript variant X4XM_011536723.2:c.N/AIntron Variant
SLC35F4 transcript variant X5XM_011536724.2:c.N/AIntron Variant
SLC35F4 transcript variant X9XM_011536725.1:c.N/AIntron Variant
SLC35F4 transcript variant X2XM_017021258.1:c.N/AIntron Variant
SLC35F4 transcript variant X8XM_017021260.1:c.N/AIntron Variant
SLC35F4 transcript variant X6XM_017021259.1:c.N/AGenic Downstream Transcript Variant
SLC35F4 transcript variant X10XM_017021261.1:c.N/AGenic Downstream Transcript Variant
SLC35F4 transcript variant X9XR_001750297.1:n.N/AIntron Variant
SLC35F4 transcript variant X11XR_001750298.1:n.N/AIntron Variant
SLC35F4 transcript variant X12XR_001750299.1:n.N/AIntron Variant
SLC35F4 transcript variant X7XR_943418.2:n.N/AIntron Variant
SLC35F4 transcript variant X10XR_943419.2:n.N/AIntron Variant

Gene: LOC105370519, uncharacterized LOC105370519(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105370519 transcriptXR_943909.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.973A=0.027
1000GenomesAmericanSub694G=0.850A=0.150
1000GenomesEast AsianSub1008G=0.963A=0.037
1000GenomesEuropeSub1006G=0.816A=0.184
1000GenomesGlobalStudy-wide5008G=0.909A=0.091
1000GenomesSouth AsianSub978G=0.900A=0.100
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.834A=0.166
The Genome Aggregation DatabaseAfricanSub8602G=0.958A=0.042
The Genome Aggregation DatabaseAmericanSub822G=0.840A=0.160
The Genome Aggregation DatabaseEast AsianSub1610G=0.965A=0.035
The Genome Aggregation DatabaseEuropeSub17992G=0.833A=0.166
The Genome Aggregation DatabaseGlobalStudy-wide29328G=0.877A=0.122
The Genome Aggregation DatabaseOtherSub302G=0.850A=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.888A=0.111
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.835A=0.165
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs116239230.000307alcohol consumption (maxi-drinks)24277619

eQTL of rs11623923 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11623923 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr145802516958025310E070-17443
chr145802612058026185E070-16568
chr145803208258032132E070-10621
chr145803217358032442E070-10311
chr145803217358032442E081-10311
chr145803277158032821E081-9932
chr145803208258032132E082-10621
chr145803217358032442E082-10311
chr145803277158032821E082-9932