rs11634491

Homo sapiens
A>G
SLC28A1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0350 (10456/29878,GnomAD)
G=0318 (9271/29118,TOPMED)
G=0398 (1991/5008,1000G)
G=0408 (1573/3854,ALSPAC)
G=0403 (1496/3708,TWINSUK)
chr15:84903829 (GRCh38.p7) (15q25.3)
AD
GWASdb2
1   publication(s)
See rs on genome
141 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.84903829A>G
GRCh37.p13 chr 15NC_000015.9:g.85447060A>G

Gene: SLC28A1, solute carrier family 28 member 1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SLC28A1 transcript variant 3NM_001287761.1:c.N/AIntron Variant
SLC28A1 transcript variant 4NM_001287762.1:c.N/AIntron Variant
SLC28A1 transcript variant 5NM_001321721.1:c.N/AIntron Variant
SLC28A1 transcript variant 6NM_001321722.1:c.N/AIntron Variant
SLC28A1 transcript variant 1NM_004213.4:c.N/AIntron Variant
SLC28A1 transcript variant 2NM_201651.2:c.N/AGenic Downstream Transcript Variant
SLC28A1 transcript variant X1XM_011522203.2:c.N/AIntron Variant
SLC28A1 transcript variant X2XM_011522204.2:c.N/AIntron Variant
SLC28A1 transcript variant X3XM_011522205.2:c.N/AIntron Variant
SLC28A1 transcript variant X4XM_011522206.2:c.N/AIntron Variant
SLC28A1 transcript variant X5XM_011522207.2:c.N/AIntron Variant
SLC28A1 transcript variant X6XM_011522208.2:c.N/AIntron Variant
SLC28A1 transcript variant X7XM_011522209.2:c.N/AIntron Variant
SLC28A1 transcript variant X10XM_011522210.2:c.N/AIntron Variant
SLC28A1 transcript variant X10XM_011522211.2:c.N/AIntron Variant
SLC28A1 transcript variant X13XM_011522212.1:c.N/AIntron Variant
SLC28A1 transcript variant X14XM_011522214.2:c.N/AIntron Variant
SLC28A1 transcript variant X15XM_011522215.2:c.N/AIntron Variant
SLC28A1 transcript variant X17XM_011522216.2:c.N/AIntron Variant
SLC28A1 transcript variant X16XM_011522217.1:c.N/AIntron Variant
SLC28A1 transcript variant X20XM_011522218.2:c.N/AIntron Variant
SLC28A1 transcript variant X11XM_017022723.1:c.N/AIntron Variant
SLC28A1 transcript variant X18XR_931944.2:n.N/AIntron Variant
SLC28A1 transcript variant X21XR_931945.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.789G=0.211
1000GenomesAmericanSub694A=0.490G=0.510
1000GenomesEast AsianSub1008A=0.625G=0.375
1000GenomesEuropeSub1006A=0.614G=0.386
1000GenomesGlobalStudy-wide5008A=0.602G=0.398
1000GenomesSouth AsianSub978A=0.400G=0.600
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.592G=0.408
The Genome Aggregation DatabaseAfricanSub8702A=0.767G=0.233
The Genome Aggregation DatabaseAmericanSub836A=0.460G=0.540
The Genome Aggregation DatabaseEast AsianSub1614A=0.623G=0.377
The Genome Aggregation DatabaseEuropeSub18426A=0.606G=0.393
The Genome Aggregation DatabaseGlobalStudy-wide29878A=0.650G=0.350
The Genome Aggregation DatabaseOtherSub300A=0.630G=0.370
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.681G=0.318
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.597G=0.403
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs116344910.000664alcohol dependence20201924

eQTL of rs11634491 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11634491 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr158542156885422174E067-24886
chr158545512085456506E0678060
chr158545654885456652E0679488
chr158547118485471757E06724124
chr158549306685493237E06746006
chr158549329285493400E06746232
chr158549361285493700E06746552
chr158549379985493869E06746739
chr158549393485494047E06746874
chr158549406785494127E06747007
chr158549413185494439E06747071
chr158540700985408084E068-38976
chr158542706185427385E068-19675
chr158545271985452780E0685659
chr158545512085456506E0688060
chr158549093285491055E06843872
chr158549119685492037E06844136
chr158549306685493237E06846006
chr158549329285493400E06846232
chr158549361285493700E06846552
chr158549379985493869E06846739
chr158549393485494047E06846874
chr158549406785494127E06847007
chr158549413185494439E06847071
chr158540700985408084E069-38976
chr158545249985452682E0695439
chr158545271985452780E0695659
chr158545282085452898E0695760
chr158545298985453083E0695929
chr158545428085454573E0697220
chr158545463185454821E0697571
chr158545499785455047E0697937
chr158545512085456506E0698060
chr158545654885456652E0699488
chr158547049985470835E06923439
chr158547090685471001E06923846
chr158547118485471757E06924124
chr158549093285491055E06943872
chr158549119685492037E06944136
chr158549238185492535E06945321
chr158549306685493237E06946006
chr158549329285493400E06946232
chr158549361285493700E06946552
chr158549379985493869E06946739
chr158549393485494047E06946874
chr158549406785494127E06947007
chr158549413185494439E06947071
chr158549457385494644E06947513
chr158549506185495387E06948001
chr158539820185398649E071-48411
chr158540700985408084E071-38976
chr158545171685451849E0714656
chr158545189885452284E0714838
chr158545232185452498E0715261
chr158545249985452682E0715439
chr158545271985452780E0715659
chr158545282085452898E0715760
chr158545298985453083E0715929
chr158545314285453383E0716082
chr158545428085454573E0717220
chr158545463185454821E0717571
chr158545499785455047E0717937
chr158545512085456506E0718060
chr158547090685471001E07123846
chr158547118485471757E07124124
chr158549042985490533E07143369
chr158549056785490657E07143507
chr158549093285491055E07143872
chr158549119685492037E07144136
chr158549238185492535E07145321
chr158549306685493237E07146006
chr158549379985493869E07146739
chr158549393485494047E07146874
chr158549406785494127E07147007
chr158549413185494439E07147071
chr158549457385494644E07147513
chr158549506185495387E07148001
chr158540700985408084E072-38976
chr158545232185452498E0725261
chr158545249985452682E0725439
chr158545271985452780E0725659
chr158545282085452898E0725760
chr158545298985453083E0725929
chr158545512085456506E0728060
chr158545654885456652E0729488
chr158547118485471757E07224124
chr158549119685492037E07244136
chr158549238185492535E07245321
chr158549306685493237E07246006
chr158549329285493400E07246232
chr158549361285493700E07246552
chr158549379985493869E07246739
chr158549393485494047E07246874
chr158549406785494127E07247007
chr158549413185494439E07247071
chr158540700985408084E073-38976
chr158545171685451849E0734656
chr158545189885452284E0734838
chr158545232185452498E0735261
chr158545249985452682E0735439
chr158545271985452780E0735659
chr158545282085452898E0735760
chr158545298985453083E0735929
chr158545393285454106E0736872
chr158545411185454253E0737051
chr158545428085454573E0737220
chr158545463185454821E0737571
chr158545499785455047E0737937
chr158545512085456506E0738060
chr158545654885456652E0739488
chr158549042985490533E07343369
chr158549056785490657E07343507
chr158549119685492037E07344136
chr158539820185398649E074-48411
chr158539873185398979E074-48081
chr158540700985408084E074-38976
chr158540827785408339E074-38721
chr158545171685451849E0744656
chr158545189885452284E0744838
chr158545232185452498E0745261
chr158545249985452682E0745439
chr158545271985452780E0745659
chr158545282085452898E0745760
chr158545298985453083E0745929
chr158545499785455047E0747937
chr158545512085456506E0748060
chr158545654885456652E0749488
chr158545666485456898E0749604
chr158547090685471001E07423846
chr158547118485471757E07424124
chr158549042985490533E07443369
chr158549056785490657E07443507
chr158549093285491055E07443872
chr158549119685492037E07444136
chr158549238185492535E07445321
chr158549306685493237E07446006
chr158549329285493400E07446232
chr158549361285493700E07446552
chr158549379985493869E07446739
chr158549406785494127E07447007
chr158549413185494439E07447071