rs11639310

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0403 (12071/29928,GnomAD)
C==0482 (14039/29118,TOPMED)
C==0401 (2006/5008,1000G)
C==0306 (1181/3854,ALSPAC)
C==0311 (1154/3708,TWINSUK)
chr15:34129750 (GRCh38.p7) (15q14)
AD
GWASdb2
1   publication(s)
See rs on genome
46 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.34129750C>T
GRCh37.p13 chr 15NC_000015.9:g.34421951C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.797T=0.203
1000GenomesAmericanSub694C=0.380T=0.620
1000GenomesEast AsianSub1008C=0.153T=0.847
1000GenomesEuropeSub1006C=0.303T=0.697
1000GenomesGlobalStudy-wide5008C=0.401T=0.599
1000GenomesSouth AsianSub978C=0.230T=0.770
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.306T=0.694
The Genome Aggregation DatabaseAfricanSub8708C=0.707T=0.293
The Genome Aggregation DatabaseAmericanSub836C=0.380T=0.620
The Genome Aggregation DatabaseEast AsianSub1618C=0.149T=0.851
The Genome Aggregation DatabaseEuropeSub18464C=0.284T=0.715
The Genome Aggregation DatabaseGlobalStudy-wide29928C=0.403T=0.596
The Genome Aggregation DatabaseOtherSub302C=0.320T=0.680
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.482T=0.517
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.311T=0.689
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs116393100.00065alcohol dependence20201924

eQTL of rs11639310 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11639310 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr153439157934391660E067-30291
chr153439167234391727E067-30224
chr153439242834392523E067-29428
chr153443475134434977E06712800
chr153447135434471451E06749403
chr153439157934391660E068-30291
chr153439167234391727E068-30224
chr153439242834392523E068-29428
chr153447135434471451E06849403
chr153447146634471516E06849515
chr153447155734471689E06849606
chr153439157934391660E069-30291
chr153439167234391727E069-30224
chr153439546734395547E069-26404
chr153447135434471451E06949403
chr153447146634471516E06949515
chr153447155734471689E06949606
chr153439157934391660E070-30291
chr153439167234391727E070-30224
chr153439242834392523E070-29428
chr153439242834392523E071-29428
chr153447135434471451E07149403
chr153447146634471516E07149515
chr153447155734471689E07149606
chr153437664434376701E072-45250
chr153439242834392523E072-29428
chr153447135434471451E07249403
chr153447146634471516E07249515
chr153447155734471689E07249606
chr153437578534375845E073-46106
chr153439028534390335E073-31616
chr153439037034390571E073-31380
chr153439157934391660E073-30291
chr153439167234391727E073-30224
chr153439242834392523E073-29428
chr153447135434471451E07349403
chr153439242834392523E074-29428
chr153447135434471451E07449403
chr153447146634471516E07449515
chr153447155734471689E07449606
chr153439157934391660E081-30291
chr153439167234391727E081-30224
chr153439242834392523E081-29428
chr153439157934391660E082-30291
chr153439167234391727E082-30224
chr153439242834392523E082-29428










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr153439333234394793E067-27158
chr153439333234394793E068-27158
chr153439333234394793E069-27158
chr153439333234394793E070-27158
chr153439333234394793E071-27158
chr153439333234394793E072-27158
chr153439333234394793E073-27158
chr153439333234394793E074-27158
chr153439333234394793E081-27158
chr153439333234394793E082-27158