rs11670215

Organism: Homo sapiens

Alleles: T>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0225 (6739/29936,GnomAD)
G=0179 (5230/29118,TOPMED)
G=0299 (1499/5008,1000G)
G=0232 (895/3854,ALSPAC)
G=0220 (814/3708,TWINSUK)

Position: chr19:51684315 (GRCh38.p7) (19q13.41)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 73 Enhancers around

Promoter: 34 Promoters around

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 19	NC_000019.10:g.51684315T>G
GRCh37.p13 chr 19	NC_000019.9:g.52187568T>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.912	G=0.088
1000Genomes	American	Sub	694	T=0.750	G=0.250
1000Genomes	East Asian	Sub	1008	T=0.344	G=0.656
1000Genomes	Europe	Sub	1006	T=0.755	G=0.245
1000Genomes	Global	Study-wide	5008	T=0.701	G=0.299
1000Genomes	South Asian	Sub	978	T=0.690	G=0.310
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.768	G=0.232
The Genome Aggregation Database	African	Sub	8722	T=0.891	G=0.109
The Genome Aggregation Database	American	Sub	836	T=0.730	G=0.270
The Genome Aggregation Database	East Asian	Sub	1612	T=0.346	G=0.654
The Genome Aggregation Database	Europe	Sub	18464	T=0.759	G=0.240
The Genome Aggregation Database	Global	Study-wide	29936	T=0.774	G=0.225
The Genome Aggregation Database	Other	Sub	302	T=0.800	G=0.200
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.820	G=0.179
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.780	G=0.220

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs11670215	0.000561	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr19	52166928	52167017	E067	-20551
chr19	52190589	52190639	E067	3021
chr19	52208611	52208919	E067	21043
chr19	52195941	52195992	E068	8373
chr19	52208611	52208919	E068	21043
chr19	52190589	52190639	E069	3021
chr19	52195941	52195992	E069	8373
chr19	52196200	52196287	E069	8632
chr19	52196550	52196853	E069	8982
chr19	52208611	52208919	E069	21043
chr19	52227228	52227424	E069	39660
chr19	52228346	52228479	E069	40778
chr19	52229231	52229752	E069	41663
chr19	52229848	52229949	E069	42280
chr19	52184479	52185127	E070	-2441
chr19	52189926	52189976	E070	2358
chr19	52190208	52190287	E070	2640
chr19	52190305	52190414	E070	2737
chr19	52190459	52190506	E070	2891
chr19	52190589	52190639	E070	3021
chr19	52196200	52196287	E070	8632
chr19	52196550	52196853	E070	8982
chr19	52160035	52160788	E071	-26780
chr19	52196200	52196287	E071	8632
chr19	52196550	52196853	E071	8982
chr19	52208611	52208919	E071	21043
chr19	52226803	52227021	E071	39235
chr19	52227024	52227139	E071	39456
chr19	52227228	52227424	E071	39660
chr19	52228346	52228479	E071	40778
chr19	52229231	52229752	E071	41663
chr19	52230347	52230973	E071	42779
chr19	52196200	52196287	E072	8632
chr19	52196550	52196853	E072	8982
chr19	52208611	52208919	E072	21043
chr19	52226803	52227021	E072	39235
chr19	52227024	52227139	E072	39456
chr19	52227228	52227424	E072	39660
chr19	52228346	52228479	E072	40778
chr19	52229231	52229752	E072	41663
chr19	52229848	52229949	E072	42280
chr19	52230347	52230973	E072	42779
chr19	52189529	52189719	E073	1961
chr19	52196200	52196287	E073	8632
chr19	52196550	52196853	E073	8982
chr19	52160035	52160788	E074	-26780
chr19	52190589	52190639	E074	3021
chr19	52195941	52195992	E074	8373
chr19	52196200	52196287	E074	8632
chr19	52208611	52208919	E074	21043
chr19	52226803	52227021	E074	39235
chr19	52227024	52227139	E074	39456
chr19	52227228	52227424	E074	39660
chr19	52228346	52228479	E074	40778
chr19	52229231	52229752	E074	41663
chr19	52229848	52229949	E074	42280
chr19	52230347	52230973	E074	42779
chr19	52190208	52190287	E081	2640
chr19	52190305	52190414	E081	2737
chr19	52190459	52190506	E081	2891
chr19	52190589	52190639	E081	3021
chr19	52195941	52195992	E081	8373
chr19	52196200	52196287	E081	8632
chr19	52196550	52196853	E081	8982
chr19	52197056	52197138	E081	9488
chr19	52197160	52197307	E081	9592
chr19	52197332	52197434	E081	9764
chr19	52197454	52197508	E081	9886
chr19	52197510	52197613	E081	9942
chr19	52198322	52198463	E082	10754
chr19	52226803	52227021	E082	39235
chr19	52227024	52227139	E082	39456
chr19	52227228	52227424	E082	39660

Promoter Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr19	52190870	52195864	E067	3302
chr19	52222505	52223240	E067	34937
chr19	52223261	52223469	E067	35693
chr19	52190870	52195864	E068	3302
chr19	52205309	52208571	E068	17741
chr19	52222505	52223240	E068	34937
chr19	52223261	52223469	E068	35693
chr19	52223504	52223564	E068	35936
chr19	52190870	52195864	E069	3302
chr19	52205309	52208571	E069	17741
chr19	52222505	52223240	E069	34937
chr19	52223261	52223469	E069	35693
chr19	52190870	52195864	E070	3302
chr19	52205309	52208571	E070	17741
chr19	52190870	52195864	E071	3302
chr19	52205309	52208571	E071	17741
chr19	52223261	52223469	E071	35693
chr19	52190870	52195864	E072	3302
chr19	52205309	52208571	E072	17741
chr19	52222505	52223240	E072	34937
chr19	52223261	52223469	E072	35693
chr19	52223504	52223564	E072	35936
chr19	52190870	52195864	E073	3302
chr19	52222505	52223240	E073	34937
chr19	52223261	52223469	E073	35693
chr19	52190870	52195864	E074	3302
chr19	52205309	52208571	E074	17741
chr19	52222505	52223240	E074	34937
chr19	52223261	52223469	E074	35693
chr19	52190870	52195864	E081	3302
chr19	52190870	52195864	E082	3302
chr19	52205309	52208571	E082	17741
chr19	52222505	52223240	E082	34937
chr19	52223261	52223469	E082	35693

rs11670215

Genomic Coordinates

Population Frequency

P-Value

eQTL of rs11670215 in Brain tissues (GTEx Analysis Release V7)

meQTL of rs11670215 in Fetal Brain

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)

Promoter Annotation (GRCh37.p13)