SNP Detail Info-rs11670669

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

MYH14 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0463 (13843/29838,GnomAD)
G==0488 (14222/29118,TOPMED)
G==0487 (2437/5008,1000G)
G==0358 (1380/3854,ALSPAC)
G==0362 (1342/3708,TWINSUK)

Position: chr19:50248541 (GRCh38.p7) (19q13.33)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 42 Enhancers around

Promoter: 10 Promoters around

Molecule type	Change	Amino acid[Codon]	SO Term
MYH14 transcript variant 1	NM_001077186.1:c.	N/A	Intron Variant
MYH14 transcript variant 3	NM_001145809.1:c.	N/A	Intron Variant
MYH14 transcript variant 2	NM_024729.3:c.	N/A	Intron Variant
MYH14 transcript variant X3	XM_006723386.3:c.	N/A	Intron Variant
MYH14 transcript variant X1	XM_011527320.2:c.	N/A	Intron Variant
MYH14 transcript variant X2	XM_011527321.2:c.	N/A	Intron Variant
MYH14 transcript variant X4	XM_011527323.2:c.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.664	A=0.336
1000Genomes	American	Sub	694	G=0.460	A=0.540
1000Genomes	East Asian	Sub	1008	G=0.456	A=0.544
1000Genomes	Europe	Sub	1006	G=0.358	A=0.642
1000Genomes	Global	Study-wide	5008	G=0.487	A=0.513
1000Genomes	South Asian	Sub	978	G=0.430	A=0.570
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.358	A=0.642
The Genome Aggregation Database	African	Sub	8678	G=0.614	A=0.386
The Genome Aggregation Database	American	Sub	834	G=0.450	A=0.550
The Genome Aggregation Database	East Asian	Sub	1616	G=0.462	A=0.538
The Genome Aggregation Database	Europe	Sub	18410	G=0.395	A=0.604
The Genome Aggregation Database	Global	Study-wide	29838	G=0.463	A=0.536
The Genome Aggregation Database	Other	Sub	300	G=0.370	A=0.630
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.488	A=0.511
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.362	A=0.638

PMID	Title	Author	Journal
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet

SNP ID	p-value	Traits	Study
rs11670669	4.24E-06	alcohol and nictotine co-dependence	20158304

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr19	50701877	50702691	E067	-49107
chr19	50705680	50705896	E067	-45902
chr19	50705960	50706010	E067	-45788
chr19	50707983	50708164	E067	-43634
chr19	50737278	50738425	E067	-13373
chr19	50701877	50702691	E068	-49107
chr19	50702742	50703031	E068	-48767
chr19	50705480	50705577	E068	-46221
chr19	50705680	50705896	E068	-45902
chr19	50705960	50706010	E068	-45788
chr19	50737278	50738425	E068	-13373
chr19	50701877	50702691	E069	-49107
chr19	50702742	50703031	E069	-48767
chr19	50705480	50705577	E069	-46221
chr19	50705680	50705896	E069	-45902
chr19	50705960	50706010	E069	-45788
chr19	50737278	50738425	E069	-13373
chr19	50701877	50702691	E070	-49107
chr19	50701877	50702691	E071	-49107
chr19	50702742	50703031	E071	-48767
chr19	50705480	50705577	E071	-46221
chr19	50705680	50705896	E071	-45902
chr19	50705960	50706010	E071	-45788
chr19	50737278	50738425	E071	-13373
chr19	50701877	50702691	E072	-49107
chr19	50702742	50703031	E072	-48767
chr19	50703096	50703168	E072	-48630
chr19	50704362	50704412	E072	-47386
chr19	50704511	50704561	E072	-47237
chr19	50705314	50705366	E072	-46432
chr19	50705480	50705577	E072	-46221
chr19	50705680	50705896	E072	-45902
chr19	50705960	50706010	E072	-45788
chr19	50737278	50738425	E072	-13373
chr19	50701877	50702691	E073	-49107
chr19	50701877	50702691	E074	-49107
chr19	50702742	50703031	E074	-48767
chr19	50705480	50705577	E074	-46221
chr19	50705680	50705896	E074	-45902
chr19	50707983	50708164	E074	-43634
chr19	50737278	50738425	E074	-13373
chr19	50707983	50708164	E082	-43634

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr19	50706058	50707700	E067	-44098
chr19	50708217	50710061	E067	-41737
chr19	50706058	50707700	E068	-44098
chr19	50706058	50707700	E069	-44098
chr19	50706058	50707700	E070	-44098
chr19	50706058	50707700	E071	-44098
chr19	50706058	50707700	E072	-44098
chr19	50706058	50707700	E073	-44098
chr19	50706058	50707700	E074	-44098
chr19	50706058	50707700	E082	-44098

rs11670669