rs11674512

Homo sapiens
A>G
LOC150935 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0385 (11548/29930,GnomAD)
A==0393 (11466/29118,TOPMED)
A==0382 (1912/5008,1000G)
A==0429 (1655/3854,ALSPAC)
A==0423 (1568/3708,TWINSUK)
chr2:239773817 (GRCh38.p7) (2p25.3)
AD
GWASdb2
1   publication(s)
See rs on genome
15 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.239773817A>G
GRCh38.p7 chr 2 fix patch HG2233_PATCHNW_011332689.1:g.76914A>G
GRCh37.p13 chr 2NC_000002.11:g.240695511A>G

Gene: LOC150935, uncharacterized LOC150935(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC150935 transcriptNR_037808.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.393G=0.607
1000GenomesAmericanSub694A=0.430G=0.570
1000GenomesEast AsianSub1008A=0.341G=0.659
1000GenomesEuropeSub1006A=0.408G=0.592
1000GenomesGlobalStudy-wide5008A=0.382G=0.618
1000GenomesSouth AsianSub978A=0.350G=0.650
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.429G=0.571
The Genome Aggregation DatabaseAfricanSub8720A=0.382G=0.618
The Genome Aggregation DatabaseAmericanSub838A=0.390G=0.610
The Genome Aggregation DatabaseEast AsianSub1616A=0.324G=0.676
The Genome Aggregation DatabaseEuropeSub18454A=0.392G=0.607
The Genome Aggregation DatabaseGlobalStudy-wide29930A=0.385G=0.614
The Genome Aggregation DatabaseOtherSub302A=0.430G=0.570
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.393G=0.606
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.423G=0.577
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs116745120.0000159alcoholismpha002891
rs116745120.0000159alcohol dependence20201924

eQTL of rs11674512 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11674512 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr27864417478644281E06721651
chr27864431978644449E06721796
chr27864448278644685E06721959
chr27864357578643907E07121052
chr27864417478644281E07121651
chr27864431978644449E07121796
chr27864448278644685E07121959
chr27864521978645411E07122696
chr27864417478644281E07221651
chr27864431978644449E07221796
chr27864448278644685E07221959
chr27864521978645411E07222696
chr27864417478644281E07421651
chr27864431978644449E07421796
chr27864448278644685E07421959