SNP Detail Info-rs11681327

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

LOC105373718 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0220 (6605/29928,GnomAD)
G=0232 (6757/29118,TOPMED)
G=0206 (1032/5008,1000G)
G=0229 (882/3854,ALSPAC)
G=0224 (832/3708,TWINSUK)

Position: chr2:160568173 (GRCh38.p7) (2q24.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.160568173A>G
GRCh37.p13 chr 2	NC_000002.11:g.161424684A>G

Molecule type	Change	Amino acid[Codon]	SO Term
LOC105373718 transcript	XR_923526.2:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.781	G=0.219
1000Genomes	American	Sub	694	A=0.600	G=0.400
1000Genomes	East Asian	Sub	1008	A=0.977	G=0.023
1000Genomes	Europe	Sub	1006	A=0.765	G=0.235
1000Genomes	Global	Study-wide	5008	A=0.794	G=0.206
1000Genomes	South Asian	Sub	978	A=0.790	G=0.210
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.771	G=0.229
The Genome Aggregation Database	African	Sub	8698	A=0.774	G=0.226
The Genome Aggregation Database	American	Sub	836	A=0.610	G=0.390
The Genome Aggregation Database	East Asian	Sub	1620	A=0.975	G=0.025
The Genome Aggregation Database	Europe	Sub	18472	A=0.773	G=0.226
The Genome Aggregation Database	Global	Study-wide	29928	A=0.779	G=0.220
The Genome Aggregation Database	Other	Sub	302	A=0.690	G=0.310
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.767	G=0.232
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.776	G=0.224

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs11681327	0.0000477	alcoholism	pha002892
rs11681327	0.000048	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs11681327