SNP Detail Info-rs11681792

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.49957256C>T
GRCh37.p13 chr 2	NC_000002.11:g.50184394C>T
NRXN1 RefSeqGene	NG_011878.1:g.1080281G>A

Gene: NRXN1, neurexin 1(minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
NRXN1 transcript variant alpha2	NM_001135659.1:c.	N/A	Intron Variant
NRXN1 transcript variant gamma1	NM_001320156.1:c.	N/A	Intron Variant
NRXN1 transcript variant gamma2	NM_001320157.1:c.	N/A	Intron Variant
NRXN1 transcript variant alpha1	NM_004801.4:c.	N/A	Intron Variant
NRXN1 transcript variant beta	NM_138735.2:c.	N/A	Intron Variant
NRXN1 transcript variant X10	XM_005264642.3:c.	N/A	Intron Variant
NRXN1 transcript variant X23	XM_005264643.3:c.	N/A	Intron Variant
NRXN1 transcript variant X31	XM_006712137.3:c.	N/A	Intron Variant
NRXN1 transcript variant X7	XM_011533167.2:c.	N/A	Intron Variant
NRXN1 transcript variant X12	XM_011533171.2:c.	N/A	Intron Variant
NRXN1 transcript variant X14	XM_011533172.2:c.	N/A	Intron Variant
NRXN1 transcript variant X20	XM_011533174.2:c.	N/A	Intron Variant
NRXN1 transcript variant X24	XM_011533175.2:c.	N/A	Intron Variant
NRXN1 transcript variant X29	XM_011533177.2:c.	N/A	Intron Variant
NRXN1 transcript variant X30	XM_011533178.2:c.	N/A	Intron Variant
NRXN1 transcript variant X44	XM_011533183.1:c.	N/A	Intron Variant
NRXN1 transcript variant X1	XM_017005303.1:c.	N/A	Intron Variant
NRXN1 transcript variant X2	XM_017005304.1:c.	N/A	Intron Variant
NRXN1 transcript variant X3	XM_017005305.1:c.	N/A	Intron Variant
NRXN1 transcript variant X4	XM_017005306.1:c.	N/A	Intron Variant
NRXN1 transcript variant X5	XM_017005307.1:c.	N/A	Intron Variant
NRXN1 transcript variant X6	XM_017005308.1:c.	N/A	Intron Variant
NRXN1 transcript variant X8	XM_017005309.1:c.	N/A	Intron Variant
NRXN1 transcript variant X9	XM_017005310.1:c.	N/A	Intron Variant
NRXN1 transcript variant X11	XM_017005311.1:c.	N/A	Intron Variant
NRXN1 transcript variant X13	XM_017005312.1:c.	N/A	Intron Variant
NRXN1 transcript variant X15	XM_017005313.1:c.	N/A	Intron Variant
NRXN1 transcript variant X16	XM_017005314.1:c.	N/A	Intron Variant
NRXN1 transcript variant X17	XM_017005315.1:c.	N/A	Intron Variant
NRXN1 transcript variant X18	XM_017005316.1:c.	N/A	Intron Variant
NRXN1 transcript variant X19	XM_017005317.1:c.	N/A	Intron Variant
NRXN1 transcript variant X21	XM_017005318.1:c.	N/A	Intron Variant
NRXN1 transcript variant X22	XM_017005319.1:c.	N/A	Intron Variant
NRXN1 transcript variant X25	XM_017005320.1:c.	N/A	Intron Variant
NRXN1 transcript variant X26	XM_017005321.1:c.	N/A	Intron Variant
NRXN1 transcript variant X27	XM_017005322.1:c.	N/A	Intron Variant
NRXN1 transcript variant X28	XM_017005323.1:c.	N/A	Intron Variant
NRXN1 transcript variant X32	XM_017005324.1:c.	N/A	Intron Variant
NRXN1 transcript variant X33	XM_017005325.1:c.	N/A	Intron Variant
NRXN1 transcript variant X34	XM_017005326.1:c.	N/A	Intron Variant
NRXN1 transcript variant X35	XM_017005327.1:c.	N/A	Intron Variant
NRXN1 transcript variant X36	XM_017005328.1:c.	N/A	Intron Variant
NRXN1 transcript variant X38	XM_017005330.1:c.	N/A	Intron Variant
NRXN1 transcript variant X40	XM_017005331.1:c.	N/A	Intron Variant
NRXN1 transcript variant X41	XM_017005332.1:c.	N/A	Intron Variant
NRXN1 transcript variant X42	XM_017005333.1:c.	N/A	Intron Variant
NRXN1 transcript variant X45	XM_017005334.1:c.	N/A	Intron Variant
NRXN1 transcript variant X46	XM_017005335.1:c.	N/A	Intron Variant
NRXN1 transcript variant X47	XM_017005336.1:c.	N/A	Intron Variant
NRXN1 transcript variant X48	XM_017005337.1:c.	N/A	Intron Variant
NRXN1 transcript variant X43	XM_006712140.3:c.	N/A	Genic Downstream Transcript Variant
NRXN1 transcript variant X39	XM_011533180.2:c.	N/A	Genic Downstream Transcript Variant
NRXN1 transcript variant X37	XM_017005329.1:c.	N/A	Genic Downstream Transcript Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.994	T=0.006
1000Genomes	American	Sub	694	C=0.850	T=0.150
1000Genomes	East Asian	Sub	1008	C=1.000	T=0.000
1000Genomes	Europe	Sub	1006	C=0.828	T=0.172
1000Genomes	Global	Study-wide	5008	C=0.918	T=0.082
1000Genomes	South Asian	Sub	978	C=0.870	T=0.130
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.838	T=0.162
The Genome Aggregation Database	African	Sub	8732	C=0.967	T=0.033
The Genome Aggregation Database	American	Sub	836	C=0.880	T=0.120
The Genome Aggregation Database	East Asian	Sub	1602	C=0.999	T=0.001
The Genome Aggregation Database	Europe	Sub	18470	C=0.817	T=0.182
The Genome Aggregation Database	Global	Study-wide	29942	C=0.872	T=0.127
The Genome Aggregation Database	Other	Sub	302	C=0.840	T=0.160
Trans-Omics for Precision Medicine	Global	Study-wide	29116	C=0.913	T=0.086
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.831	T=0.169

PMID	Title	Author	Journal
23942779	A genome-wide association study of behavioral disinhibition.	McGue M	Behav Genet

P-Value

SNP ID	p-value	Traits	Study
rs11681792	4E-07	alcohol dependence	23942779

eQTL of rs11681792 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs11681792 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Enhancer Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	50151636	50151875	E067	-32519
chr2	50176023	50176133	E067	-8261
chr2	50186749	50187477	E067	2355
chr2	50187688	50187876	E067	3294
chr2	50188303	50188437	E067	3909
chr2	50186749	50187477	E068	2355
chr2	50187688	50187876	E068	3294
chr2	50233787	50234137	E068	49393
chr2	50234139	50234199	E068	49745
chr2	50151039	50151089	E069	-33305
chr2	50151218	50151303	E069	-33091
chr2	50151328	50151542	E069	-32852
chr2	50185546	50185644	E069	1152
chr2	50186545	50186595	E069	2151
chr2	50186749	50187477	E069	2355
chr2	50187688	50187876	E069	3294
chr2	50199315	50199403	E069	14921
chr2	50188303	50188437	E070	3909
chr2	50199838	50200263	E070	15444
chr2	50186749	50187477	E071	2355
chr2	50188303	50188437	E071	3909
chr2	50199315	50199403	E071	14921
chr2	50141520	50141749	E072	-42645
chr2	50175379	50175429	E072	-8965
chr2	50177800	50178167	E072	-6227
chr2	50186749	50187477	E072	2355
chr2	50199315	50199403	E072	14921
chr2	50141047	50141468	E073	-42926
chr2	50187688	50187876	E073	3294
chr2	50188303	50188437	E073	3909
chr2	50177800	50178167	E074	-6227
chr2	50186749	50187477	E074	2355
chr2	50188303	50188437	E074	3909
chr2	50199838	50200263	E074	15444
chr2	50200584	50200634	E074	16190
chr2	50200670	50200720	E074	16276
chr2	50181617	50181671	E081	-2723
chr2	50185546	50185644	E081	1152
chr2	50188303	50188437	E081	3909
chr2	50199315	50199403	E081	14921
chr2	50199838	50200263	E081	15444
chr2	50200584	50200634	E081	16190
chr2	50200670	50200720	E081	16276
chr2	50185546	50185644	E082	1152
chr2	50186545	50186595	E082	2151
chr2	50186749	50187477	E082	2355

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr2	50201042	50201620	E067	16648
chr2	50201042	50201620	E068	16648
chr2	50201042	50201620	E069	16648
chr2	50201042	50201620	E070	16648
chr2	50201042	50201620	E071	16648
chr2	50201042	50201620	E072	16648
chr2	50201042	50201620	E073	16648
chr2	50201042	50201620	E074	16648
chr2	50201042	50201620	E081	16648
chr2	50201042	50201620	E082	16648

rs11681792

Genomic Coordinates

Gene: NRXN1, neurexin 1(minus strand)

Population Frequency

P-Value

eQTL of rs11681792 in Brain tissues (GTEx Analysis Release V7)

meQTL of rs11681792 in Fetal Brain

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)

Promoter Annotation (GRCh37.p13)