rs11682404

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0139 (4154/29842,GnomAD)
G=0183 (5335/29118,TOPMED)
G=0153 (767/5008,1000G)
G=0073 (282/3854,ALSPAC)
G=0084 (310/3708,TWINSUK)
chr2:230710181 (GRCh38.p7) (2q37.1)
AD
GWASdb2
1   publication(s)
See rs on genome
85 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.230710181A>G
GRCh37.p13 chr 2NC_000002.11:g.231574896A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.624G=0.376
1000GenomesAmericanSub694A=0.920G=0.080
1000GenomesEast AsianSub1008A=0.933G=0.067
1000GenomesEuropeSub1006A=0.922G=0.078
1000GenomesGlobalStudy-wide5008A=0.847G=0.153
1000GenomesSouth AsianSub978A=0.930G=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.927G=0.073
The Genome Aggregation DatabaseAfricanSub8694A=0.697G=0.303
The Genome Aggregation DatabaseAmericanSub838A=0.930G=0.070
The Genome Aggregation DatabaseEast AsianSub1620A=0.974G=0.026
The Genome Aggregation DatabaseEuropeSub18388A=0.924G=0.075
The Genome Aggregation DatabaseGlobalStudy-wide29842A=0.860G=0.139
The Genome Aggregation DatabaseOtherSub302A=0.880G=0.120
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.816G=0.183
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.916G=0.084
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs116824040.00027alcohol dependence20201924
rs116824040.00031alcohol dependence(Early onset)20201924

eQTL of rs11682404 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11682404 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2231580545231580595E0675649
chr2231582211231582261E0677315
chr2231582286231582469E0677390
chr2231582481231582658E0677585
chr2231582802231583082E0677906
chr2231584571231584661E0679675
chr2231584774231584855E0679878
chr2231602916231603530E06728020
chr2231623947231624121E06749051
chr2231580545231580595E0685649
chr2231582211231582261E0687315
chr2231582286231582469E0687390
chr2231582481231582658E0687585
chr2231600670231600765E06825774
chr2231602195231602249E06827299
chr2231602514231602906E06827618
chr2231602916231603530E06828020
chr2231615732231616286E06840836
chr2231623947231624121E06849051
chr2231624214231624407E06849318
chr2231528827231529058E069-45838
chr2231529518231529647E069-45249
chr2231555331231555518E069-19378
chr2231580545231580595E0695649
chr2231582286231582469E0697390
chr2231582481231582658E0697585
chr2231582802231583082E0697906
chr2231602916231603530E06928020
chr2231615732231616286E06940836
chr2231623345231623504E06948449
chr2231623512231623891E06948616
chr2231623947231624121E06949051
chr2231624214231624407E06949318
chr2231580545231580595E0705649
chr2231623947231624121E07049051
chr2231528827231529058E071-45838
chr2231533864231533993E071-40903
chr2231534078231534118E071-40778
chr2231534180231534340E071-40556
chr2231580805231580875E0715909
chr2231582211231582261E0717315
chr2231582286231582469E0717390
chr2231582481231582658E0717585
chr2231582802231583082E0717906
chr2231602916231603530E07128020
chr2231615732231616286E07140836
chr2231616417231616469E07141521
chr2231621875231621956E07146979
chr2231622073231622215E07147177
chr2231622270231622438E07147374
chr2231580545231580595E0725649
chr2231580805231580875E0725909
chr2231582286231582469E0727390
chr2231582481231582658E0727585
chr2231582802231583082E0727906
chr2231602916231603530E07228020
chr2231615732231616286E07240836
chr2231620627231621187E07245731
chr2231623512231623891E07248616
chr2231623947231624121E07249051
chr2231555760231556208E073-18688
chr2231580545231580595E0735649
chr2231582211231582261E0737315
chr2231582286231582469E0737390
chr2231582481231582658E0737585
chr2231617518231617727E07342622
chr2231623345231623504E07348449
chr2231623512231623891E07348616
chr2231623947231624121E07349051
chr2231624214231624407E07349318
chr2231580545231580595E0745649
chr2231582286231582469E0747390
chr2231582481231582658E0747585
chr2231582802231583082E0747906
chr2231584571231584661E0749675
chr2231584774231584855E0749878
chr2231602514231602906E07427618
chr2231602916231603530E07428020
chr2231615732231616286E07440836
chr2231623345231623504E07448449
chr2231623512231623891E07448616
chr2231623947231624121E07449051
chr2231555331231555518E081-19378
chr2231580545231580595E0815649
chr2231555331231555518E082-19378










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr2231576818231579281E0671922
chr2231576818231579281E0681922
chr2231576818231579281E0691922
chr2231576818231579281E0701922
chr2231576818231579281E0711922
chr2231576818231579281E0721922
chr2231576818231579281E0731922
chr2231576818231579281E0741922
chr2231576818231579281E0811922
chr2231576818231579281E0821922