rs11688290

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0363 (10833/29798,GnomAD)
T=0280 (8171/29118,TOPMED)
T=0267 (1335/5008,1000G)
T=0442 (1705/3854,ALSPAC)
T=0444 (1648/3708,TWINSUK)
chr2:139051336 (GRCh38.p7) (2q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.139051336C>T
GRCh37.p13 chr 2NC_000002.11:g.139808906C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.928T=0.072
1000GenomesAmericanSub694C=0.640T=0.360
1000GenomesEast AsianSub1008C=0.655T=0.345
1000GenomesEuropeSub1006C=0.596T=0.404
1000GenomesGlobalStudy-wide5008C=0.733T=0.267
1000GenomesSouth AsianSub978C=0.760T=0.240
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.558T=0.442
The Genome Aggregation DatabaseAfricanSub8704C=0.871T=0.129
The Genome Aggregation DatabaseAmericanSub832C=0.620T=0.380
The Genome Aggregation DatabaseEast AsianSub1542C=0.701T=0.299
The Genome Aggregation DatabaseEuropeSub18420C=0.521T=0.478
The Genome Aggregation DatabaseGlobalStudy-wide29798C=0.636T=0.363
The Genome Aggregation DatabaseOtherSub300C=0.610T=0.390
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.719T=0.280
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.556T=0.444
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs116882903.18E-05alcohol dependence21703634

eQTL of rs11688290 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11688290 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.