rs11691730

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0209 (6274/29890,GnomAD)
A=0254 (7403/29116,TOPMED)
A=0270 (1354/5008,1000G)
A=0143 (550/3854,ALSPAC)
A=0128 (474/3708,TWINSUK)
chr2:102944668 (GRCh38.p7) (2q12.1)
ND
GWASdb2
1   publication(s)
See rs on genome
20 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.102944668G>A
GRCh37.p13 chr 2NC_000002.11:g.103561126G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.601A=0.399
1000GenomesAmericanSub694G=0.790A=0.210
1000GenomesEast AsianSub1008G=0.711A=0.289
1000GenomesEuropeSub1006G=0.843A=0.157
1000GenomesGlobalStudy-wide5008G=0.730A=0.270
1000GenomesSouth AsianSub978G=0.760A=0.240
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.857A=0.143
Trans-Omics for Precision MedicineGlobalStudy-wide29116G=0.745A=0.254
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.872A=0.128
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs116917304.65E-05alcohol and nictotine co-dependence20158304

eQTL of rs11691730 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs11691730 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2103592344103593549E06831218
chr2103593710103594123E06832584
chr2103596138103596188E06935012
chr2103592344103593549E07031218
chr2103593710103594123E07032584
chr2103595206103595439E07134080
chr2103596138103596188E07135012
chr2103596138103596188E07235012
chr2103596138103596188E07435012
chr2103548964103549294E081-11832
chr2103590416103590470E08129290
chr2103590754103590992E08129628
chr2103592344103593549E08131218
chr2103594485103594929E08133359
chr2103596138103596188E08135012
chr2103590416103590470E08229290
chr2103590754103590992E08229628
chr2103592344103593549E08231218
chr2103593710103594123E08232584
chr2103609782103609863E08248656








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr2103594177103594428E08133051